IMRT is a well-known and widely used treatment technique for carcinoma of the prostate (PCa) because it permits dose escalation to tumour while sparing normal tissues. In Sri Lanka, along with IMRT, 3DCRT also in PCa. This study was carried out compare against Simultaneous- Integrated Boost Intensity Modulated Radiation Therapy (SIB-IMRT), Sequential Standard using dosimetric parameters such as...

BACKGROUND To evaluate the impact of image-guided radiation therapy (IGRT) versus non-image-guided radiation therapy (non-IGRT) on the dose to the clinical target volume (CTV) and the cervical spinal cord during fractionated intensity-modulated radiation therapy (IMRT) for head-and-neck cancer (HNC) patients. MATERIAL AND METHODS For detailed investigation, 4 exemplary patients with daily con...

Radiotherapy efficacy is often limited by normal tissue toxicity. Standard models to estimate Normal Tissue Complication Probability (NTCP), such as Lyman-Kutcher-Burman (LKB), often rely on parameters derived from the dose-volume histograms (DVHs) which consider organs and tissues to be completely homogeneous with equal sub-volume radiation sensitivities. As a result, they neglect any potentia...

introduction: radiation therapy following breast conserving surgery is one of the most common procedures performed in any radiation oncology department. a tangential parallel-opposed pair is almost always the technique of choice for this purpose. this technique is often performed based on 3d treatment planning. the aim of this study was to compare 3d treatment planning for two different energie...

Background: HDR brachytherapy is one of the commonest methods of nasopharyngeal cancer treatment. In this method, depending on how advanced one tumor is, 2 to 6 Gy dose as intracavitary brachytherapy is prescribed. Due to high dose rate and tumor location, accuracy evaluation of treatment planning system (TPS) is particularly important. Common methods used in TPS dosimetry are based on computat...

PURPOSE Treatment planning for radiation therapy involves trade-offs with respect to different clinical goals. Typically, the dose distribution is evaluated based on few statistics and dose-volume histograms. Particularly for stereotactic treatments, the spatial dose distribution represents further criteria, e.g., when considering the gradient between subregions of volumes of interest. The auth...

Purpose: The purpose of this work is to study and quantify the differences in calculated dose computed with two algorithms available in treatment planning systems: Pencil Beam Convolution and Clarkson. Material and Methods: Four different types of treatment cases were analyzed: lung, head and neck, brain and prostate. For each case, the volume definition was based on a clinical CT-scan acquisit...