Introduction: SBRT is an emerging radiotherapy technique for treating early-stage non-small cell lung cancers (NSCLC) or oligometastatic lesions to the lung [3, 4]. Significant tumor shrinkage has been observed in some patients during the course of SBRT [1, 2]. Adaptive planning has the potential to reduce radiation dose to organs of risk (OARs), and further escalate radiation dose to the tumor...

The aim of the this study was to validate the use of an average intensity projection (AIP) for volumetric-modulated arc therapy for stereotactic body radiation therapy (VMAT-SBRT) planning for a moving lung tumor located near the diaphragm. VMAT-SBRT plans were created using AIPs reconstructed from 10 phases of 4DCT images that were acquired with a target phantom moving with amplitudes of 5, 10...

PURPOSE The objective of this study was to evaluate the dosimetric feasibility of using hippocampus (HPC) sparing intensity-modulated radiotherapy (IMRT) in patients with locally advanced nasopharyngeal carcinoma (NPC). MATERIALS/METHODS Eight cases of either T3 or T4 NPC were selected for this study. Standard IMRT treatment plans were constructed using the volume and dose constraints for the...

Three dimensional planning for high-dose-rate (HDR) brachytherapy in cervical cancer has been highly recommended by consensus guidelines such as the American Brachytherapy Society (ABS) and the Groupe Européen de Curiethérapie - European Society for Radiotherapy and Oncology (GEC-ESTRO). In this document, we describe our experience with computed tomography (CT)-based planning using the tandem/r...

PURPOSE We compared dosimetry and clinical toxicity for 3-dimensional conformal radiotherapy (3D-crt), intensity-modulated radiotherapy (imrt), and RapidArc (Varian Medical Systems, Palo Alto, CA, U.S.A.) in locally advanced pancreatic cancer (lapcc). We hypothesized that the technique with better sparing of organs at risk (oars) and better target dose distributions could lead to decreased clin...

OBJECTIVES To compare treatment plans for helical tomotherapy (TOMO), volumetric modulated arc therapy (VMAT) and intensity-modulated radiotherapy (IMRT) for locally advanced rectal cancer (LARC). MATERIALS AND METHODS This retrospective study from December 2010 to June 2013 included 20 patients with LARC who received neoadjuvant concurrent chemoradiotherapy (CCRT) with radiation doses of gre...

Target coverage and organ-at-risk sparing were compared for 22 pediatric patients with primary brain tumors treated using two distinct nozzles in pencil beam scanning (PBS) proton therapy. Consecutive patients treated at our institution using a PBS-dedicated nozzle (DN) were replanned using a universal nozzle (UN) beam model and the original DN plan objectives. Various cranial sites were treate...

The purpose of this study was to compare three computed tomography (CT) images under different conditions-average intensity projection (AIP), free breathing (FB), mid-ventilation (MidV)-used for radiotherapy contouring and planning in lung cancer patients. Two image sets derived from four-dimensional CT (4DCT) acquisition (AIP and MidV) and three-dimensional CT with FB were generated and used t...

Cardiac radioablation has emerged as a novel approach for the treatment of refractory scar-related ventricular tachycardia (VT). Current clinical evidence this is limited to photon treatments. and extracardiac radiation dose distributions in humans treated VT with proton beam therapy have not been previously reported. To evaluate target myocardium organs-at-risk (OAR) intensity modulated (IMPT)...