Sixteen patients with steroid responsive nephrotic syndrome were treated on 29 separate occasions with a low dose of prednisolone (30 mg/m2/day). All went into remission within 14 days. The duration of remission in the six patients who had had previous relapses treated with a higher dose of prednisolone was similar.

OBJECTIVE To assess the effect of high dose inhaled corticosteroids on skin. DESIGN Cross sectional study of patients receiving treatment for chest diseases. SETTING Outpatient chest clinic in a teaching hospital. PATIENTS 68 Patients divided into four groups of similar age--namely, 15 receiving long term oral prednisolone, 21 receiving high dose inhaled corticosteroids, 15 receiving low ...

1. Prednisolone is a synthetic glucocorticosteroid. In veterinary medicine, prednisolone (as the free alcohol) is included as an ingredient in a number of antibiotic preparations, which are indicated for intramammary administration for the treatment of bovine mastitis. The usual dose corresponds to 10 mg prednisolone per infected quarter. Treatment may be repeated at 12-hour intervals for a max...

Eighteen patients with polymyalgia rheumatica had corticosteroid treatment withdrawn abruptly under close observation. In each case polymyalgic symptoms reappeared but were controlled rapidly when prednisolone was reintroduced. Prednisolone withdrawal was then started by slow decrements of dose. In no patient was it possible to withdraw prednisolone treatment, after using either method, during ...

OBJECTIVE To test the hypothesis that the administration of aspirin, acetaminophen, meloxicam, celecoxib, and prednisolone have no effect on root resorption and tooth movement. MATERIALS AND METHODS A mesial force of 50 g was applied to the left maxillary first molars of sixty 10-week-old male Wistar rats using nickel titanium closed coil springs attached to the cervical area of the incisors....

We thank Dr Smith for alerting readers and us to the existence of his excellent paper that came out after our study was done and during the preparation of our manuscript. Our study described asymptomatic subjects, a somewhat different group from that in Dr Smith’s study—namely, patients with unexplained knee pain with clinically and arthroscopically normal knee joints. It is fascinating that in...

BACKGROUND Evidence for disease modifying activity of low dose corticosteroid treatment in rheumatoid arthritis is contradictory. Studies showing radiological benefit suggest that continued treatment is required to sustain the effect. OBJECTIVE To evaluate the effect of low dose oral prednisolone in early rheumatoid arthritis on disease activity over two years. DESIGN Double blind placebo c...

Th incidence and severity of posterior subcapsular cataracts were studied in 58 children with steroid-sensitive nephrotic syndrome. Eight (14%) children had cataracts. Visual acuity was normal in all but one child. There was no relationship between total dose or mean daily dose of prednisolone (corrected for body surface area) and cataract formation. Alternate-day treatment with prednisolone fo...

BACKGROUND AND AIMS Endoscopic submucosal dissection (ESD) was developed in Japan and has been performed on many patients with early stage esophageal cancer; however quality of life in patients with postoperative stricture is drastically decreased and repeat, periodic endoscopic balloon dilatation (EBD) is usually required over long periods. In this study, we evaluate the efficacy of short peri...