نتایج جستجو برای: dosage adjustment

تعداد نتایج: 174828  

Journal: :Journal of the American Medical Informatics Association 2009

Journal: :International journal for quality in health care : journal of the International Society for Quality in Health Care 2003
L Salomon G Deray M C Jaudon C Chebassier P Bossi V Launay-Vacher B Diquet J M Ceza S Levu G Brücker P Ravaud

OBJECTIVES The potential consequences of medication misuse in renal impairment have not been assessed in a population of in-patients. The purpose of this study was to determine the frequency and potential consequences of a lack of dosage adjustment in hospitalized patients with renal impairment. DESIGN Order sheets for in-patients having a creatinine above 0.7 mg/dl were analysed. We consider...

Journal: :Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences) 2004

Journal: :Clinical pharmacokinetics 2011
Hafedh Marouani Anastasios Zografidis Athanassios Iliadis

BACKGROUND AND OBJECTIVES Therapeutic drug monitoring is applied to a range of drugs. To predict an appropriate dosing regimen, models based on Bayesian techniques have been used. However, this approach requires a well trained professional and sophisticated software. The objectives of this study were first to develop kinetic nomograms as a useful tool to achieve individual drug blood concentrat...

Journal: :Anaesthesiology intensive therapy 2012
Wiesława Duszyńska

The antibiotic treatment of severe sepsis poses an increasing challenge in ICU. The multidrug resistance and diverse pharmacokinetics of antibiotics requires a different approach on antibiotic therapy because of the inadequate serum antibiotic levels found in ICU patients. The current guidelines or recommendations of antibiotic treatment take into account the pharmacokinetic parameters in deter...

Journal: :Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 2012
Leonor Periáñez-Párraga Iciar Martínez-López Pere Ventayol-Bosch Francesc Puigventós-Latorre Olga Delgado-Sánchez

Chronic liver diseases (CLD) alter the kinetics of drugs. Despite dosage adjustment is based on Child-Pugh scores, there are no available recommendations and/or algorithms of reference to facilitate dosage regimens. A literature review about dose adjustment of the drugs from the hospital guide -which are included in the list of the WHO recommended drugs to be avoided or used with caution in pat...

Journal: :Circulation. Arrhythmia and electrophysiology 2017
Jae Hyung Cho So Jin Youn JoEllyn C Moore Roxanne Kyriakakis Carolyn Vekstein Michael Militello Stacy M Poe Kathy Wolski Patrick J Tchou Niraj Varma Mark J Niebauer Mandeep Bhargava Walid I Saliba Oussama M Wazni Bruce D Lindsay Bruce L Wilkoff Mina K Chung

BACKGROUND Although dofetilide labeling states that the drug must be initiated or reinitiated with continuous electrocardiographic monitoring and in the presence of trained personnel, the risks of dofetilide reloading justifying repeat hospitalization have not been investigated. METHODS AND RESULTS Patients admitted for dofetilide reloading for atrial arrhythmias were retrospectively reviewed...

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