background: the progressive accumulation of misfolded and aggregated proteins in neurons is an accepted mechanism in aging. overproduction of reactive oxygen species (ros), referred to as oxidative stress, is currently believed to play a pivotal role in this process. lipofuscin as a histological index of aging results from cross-links between oxidized proteins and lipids. therefore, to attenuat...

background: reactive oxygen species (ros) are a group of free radicals that in excessive amounts have negative influence on sperm quality and function. objective: to study the effect of varicocele and its severity on the level of ros in infertile men with clinical varicocele. materials and methods: in this controlled prospective study, 42 men with clinically diagnosed left varicocele and 30 fer...

background: reactive oxygen species (ros) are a group of free radicals that in excessive amounts have negative influence on sperm quality and function. objective: we compared ros levels in seminal plasma of infertile men with this level in healthy donors. we also determined the ros level in semen of infertile men according to the etiology of infertility, and also the effect of smoking on its le...

objective: oxidative stress plays a key role in the pathophysiology of brain ischemia and neurodegenerative disorders.previous studies indicated that viola tricolor and viola odorataare rich sources of antioxidants. this study aimed to determine whether these plants protect neurons against serum/glucose deprivation (sgd)-induced cell death in an in vitro model of ischemia and neurodegeneration....

background: induction of cellular response after exposure to electromagnetic fields is limited to coherent fields. an incoherent noise field is supposed to suppress the bioeffects of regular rf electromagnetic fields. the purpose of this study was to investigate the effect of gsm mobile phone-induced radiofrequency (rf) on the induction of oxidative stress in sp2/0 cell line. materials and meth...

brucellosis is an infectious disease with high impact on innate immune responses which is induced partly by its dna. in the present study the potential differences of wild type and patients isolates versus attenuated vaccine strains in terms of cytokines, ros and no induction on murine splenocytes and peritoneal macrophages were investigated. this panel varied in base composition and included d...

metals can cause oxidative stress by increasing the formation of reactive oxygen species (ros), which make antioxidants incapable of defiance against growing amounts of free radicals. metal toxicity is related to their oxidative state and reactivity with other compounds. however, several reports about metals have been published in the recent years. mitochondria, as a site of cellular oxygen con...