BACKGROUND Although allogeneic hematopoietic cell transplantation (HCT) has a potential to cure patients with paroxysmal nocturnal hemoglobinuria (PNH), appropriate indication and conditioning regimen for HCT have not been established. PATIENTS AND METHODS Between July 1999 and December 2001, five patients with PNH underwent allogeneic HCT: three for refractory hemolysis and two for aggravati...

BACKGROUND Donor obesity, defined as donor body mass index (D-BMI) of 30 kg/m or greater, has been associated with increased risk of technical failure and poor pancreas allograft outcomes. Many transplant centers establish a threshold of D-BMI of 30 kg/m to decline donor offers for pancreas transplantation. However, no previous studies differentiate the impact of mild (D-BMI, 30-35 kg/m) versus...

Various electron-rich aromatic and olefinic donors (D) are readily converted to their cation radicals (D!!) in the presence of strong protic acids, even in nonpolar solvents such as dichloromethane. By using the three prototypical organic donors octamethylbiphenylene (OMB), adamantylideneadamantane (AA) and the isomeric fused homoadamantene (FHA), we identify the protonated donor (D-H) as the e...

In a list exchange (LE), the intended recipient in an incompatible pair receives priority on the deceased donor waitlist (DD-waitlist) after the paired incompatible donor donates a kidney to a DD-waitlist candidate. A nondirected donor's (ND-D) kidney is usually transplanted directly to a DD-waitlist candidate. These two established practices would help even more transplant candidates if they w...

Donor polymer PBDB-T and acceptor PF5-Y5 form D–A complexes in solution, as confirmed by combined absorption, excitation, emission spectroscopy of blend solutions.

Cytomegalovirus (CMV) remains a significant cause of morbidity after allogeneic hematopoietic stem cell transplantation (HSCT). Clinical risk varies according to a number of factors, including recipient/donor CMV serostatus. Current dogma suggests risk is greatest in seropositive recipient (R+)/seronegative donor (D-) transplants and is exacerbated by T-cell depletion. We hypothesized that in t...

The DFT approach of Becke's three-parameter compound (B3LYP) was employed in all studies triphenylamine (TPA) molecules as a donor (D) for solar cell applications this work.

A carbene-catalyzed formal umpolung of donor–acceptor (D–A) cyclopropanes is disclosed with chiral spirocyclic lactones bearing multiple functional groups afforded excellent enantio- and diastereoselectivities.

Charge Transfer (CT) complexes formed between dibenzo-24-crown-8 (DB24C8) as an electron donor with the σ-electron acceptor iodine (I2) in chloroform, dichloromethane, and 1,2-dichloroethane solutions have been studied by different spectroscopic techniques at room temperature. The spectral studies of the complexes were det...