نتایج جستجو برای: dna profiling
تعداد نتایج: 574125 فیلتر نتایج به سال:
Nowadays, in genomocentric era accelerated research of the human genome coupled with advances is enabling the comprehensive molecular profiling of human tissue. Particularly, DNA microarrays are powerful tools for obtaining global view of human non-Hodgkin lymphomas gene expression. Complex information from lymphomas “expression profiling” studies can, in turn, be used to create molecular marke...
Comparative genomic hybridization by means of BAC microarrays (array CGH) allows high-resolution profiling of copy-number aberrations in tumor DNA. However, specific genetic lesions associated with small but clinically relevant tumor areas may pass undetected due to intra-tumor heterogeneity and/or the presence of contaminating normal cells. Here, we show that the combination of laser capture m...
The molecular profiling of circulating tumor DNA (ctDNA) is a helpful tool not only in cancer treatment, but also the early detection relapse. However, clinical interpretation ctDNA negative result remains challenging. characterization nucleosomes (carrying cell-free DNA) and associated epigenetic modifications (playing key role tumorigenesis different cancers) may provide useful information fo...
DNA methylation is a type of epigenetic changes that directly affects DNA. In mammals, DNA methylation is essential for fetal development and stem cell differentiation and this phenomenon essentially occurs within the CpG islands. In this study, two methods were used to study the DNA methylation profile of cow genome. In the first method, the DNA methylation profile of the differentially expres...
Motivation: This paper investigates the log ratio calculations for DNA array experiments using two color dyes. It is shown
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