Sugar parts play important roles in recognizing molecules on the cell membranes. We successfully produced sugar-type micellar surfactants, lactonoalkylamide (LacCn), for the first time. Spherical vesicles, three-component hybrid liposomes, were obtained after the sonication of the mixture of L-alpha-dimyristoyl-phosphatidylcholine (DMPC), Tween 20 and LacCn (DMPC:Tween 20:LacCn=65:7:28). It is ...

Hydrophobic matching, in which transmembrane proteins cause the surrounding lipid bilayer to adjust its hydrocarbon thickness to match the length of the hydrophobic surface of the protein, is a commonly accepted idea in membrane biophysics. To test this idea, gramicidin (gD) was embedded in 1, 2-dilauroyl-sn-glycero-3-phosphocholine (DLPC) and 1, 2-myristoyl-sn-glycero-3-phosphocholine (DMPC) b...

We have previously described the interactions of aquaporin-0 (AQP0) with dimyristoyl phosphatidylcholine (DMPC) lipids. We have now determined the 2.5 A structure of AQP0 in two-dimensional (2D) crystals formed with Escherichia coli polar lipids (EPLs), which differ from DMPC both in headgroups and acyl chains. Comparison of the two structures shows that AQP0 does not adapt to the different len...

The interfacial properties of the negatively charged dimyristoyl-phosphatidylglycerol (DMPG) and the zwitterionic dimyristoyl-phosphatidylcholine (DMPC) vesicles mixed with the fusion inhibitor lysomyristoylphosphatidylcholine (LMPC) are investigated by electron paramagnetic resonance (EPR). At 35 degrees C, addition of 20 mol% of LMPC to the DMPG vesicles increases the effective concentration ...

Electron spin resonance (ESR) spectroscopy was used to study the penetration and interaction of bee venom melittin with dimyristoylphosphatidylcholine (DMPC) and ditetradecylphosphatidylglycerol (DTPG) bilayer membranes. Melittin is a surface-active, amphipathic peptide and serves as a useful model for a variety of membrane interactions, including those of presequences and signal peptides, as w...

This paper proposes an automatic model decomposition approach for decentralized model predictive control (DMPC) of drinking water networks (DWNs). For a given DWN, the proposed algorithm partitions the network in a set of subnetworks by taking advantage of the topology of the network, of the information about the use of actuators, and of system management heuristics. The derived suboptimal DMPC...

In this paper, a hierarchical and decentralised model predictive control (DMPC) strategy for drinking water networks (DWN) is proposed. The DWN is partitioned in a set of subnetworks using a partitioning algorithm that makes use of the topology of the network, historic information about the actuator usage and heuristics. A suboptimal DMPC strategy was derived, which consists in a set of MPC con...

Quantitative structures of the fully hydrated fluid phases of dimyristoylphosphatidylcholine (DMPC) and dilauroylphosphatidylcholine (DLPC) were obtained at 30 degrees C. Data for the relative form factors F(q(z)) for DMPC were obtained using a combination of four methods. 1), Volumetric data provided F(0). 2), Diffuse x-ray scattering from oriented stacks of bilayers provided relative form fac...

objective(s):development of new generation of vaccines against leishmaniasis is possible because long-term protection is usually seen after recovery from cutaneous leishmaniasis. iscomatrix is particulate antigen delivery system composed of antigen, cholesterol, phospholipid and saponin. in this study, the role of iscomatrix bilayer composition made by different phase transition temperature (tc...

1H NMR spectroscopic studies have been carried out for multidispersed vesicles of DMPC and DOPC in the presence of Eu(NO3)3 and anesthetics (tetracaine and lidocaine). 1H NMR signals of DMPC vesicles disappeared, while those of DOPC did not, in the coexistence of Eu(NO3)3 and the anesthetics. An addition of EDTA-Na4 to this solution regained the signals of DMPC vesicles, implying cancellation o...