diabetic macular edema (dme) is an important cause of blindness in the working population and is currently challenging to treat. current interventions include focal laser or intravitreal injections. this article outlines a new treatment protocol based on the concept that peripheral ischemia is the introduction to angiogenesis, that will ultimately gather its momentum at the fovea. performing ex...

Distributed mutual-exclusion (DME) circuits are an interesting example of asynchronous circuits. They are composed of identical DME cells connected in a ring of arbitrary size. Each DME cell provides a connection point for one user, and all users compete for exclusive access to a shared resource. This paper reports about formal verification of two well-known DME circuit implementations. Externa...

macular edema following diabetic retinopathy is one of the ocular complications associated with diabetes, and it is the leading cause of visual loss in the active young and middle aged population in developed countries. while all patients with diabetes particularly those with diabetic retinopathy are at increased risk of developing eye complications, early detection and timely intervention may ...

Purpose To investigate the association between hyperreflective dots (HRDs) on spectral-domain optical coherence tomography (SD-OCT) and response to intravitreal bevacizumab (IVB) or dexamethasone injection in eyes with diabetic macular edema (DME) or macular edema due to retinal vein occlusion (RVO). Methods A retrospective review was conducted involving patients with DME or macular edema due...

INTRODUCTION The pathophysiology of diabetic macular edema (DME) is complex, involving vascular endothelial growth factor (VEGF) and other inflammatory mediators. DME is currently treated first-line with intravitreal anti-VEGF treatments, though some cases are refractory to multiple anti-VEGF treatments. AREAS COVERED This article examines the evolution of treatment practices for DME, with di...

In the Federal Aviation Administration's (FAA) performance based navigation strategy announced in 2016, the FAA stated that it would retain and expand the Distance Measuring Equipment (DME) infrastructure to ensure resilient aircraft navigation capability during the event of a Global Navigation Satellite System (GNSS) outage. However, the main drawback of the DME as a GNSS back up system is tha...

Diabetic macular edema (DME) is an eye disease that belongs to diabetic retinopathy which leads to vision loss. DME, which is a swelling in the macular region of eye is a common vision problem seen in diabetic patients.Hard exudates (bright lesions)in the fundus image indicates the presence of DME. When blood vessels in retina of diabetic patient is begin to leak into the macula region of eye l...

Organoiron Complexes, Olefin Isomerization, 1,2-Dimethoxyethylene Displacement of 2-methvlpropene from [Fp(Me2C = CH2)]BF4 (Fp = (/?5-C5H5)Fe(CO)2) by Z-1,2-dimethoxyethylene (Z-DME) gives [Fp(Z-DME)]BF4. Displacement by E-1,2dimethoxyethylene (E-DME), in contrast, does not give the expected complex of E-DME, but rather the complex of the Z-alkene. A mechanism involving scission of the C = C bo...

Diabetic macular edema (DME) is a leading cause of vision loss in older Americans. Thermal laser treatment remains the mainstay of treatment for DME. Recently, alternative primary treatments for DME have been evaluated. These treatments include intravitreal injections of steroids as well as pharmaceuticals containing antibodies against vascular endothelial growth factor (VEGF). Surgical treatme...

We isolated mutations in Arabidopsis to understand how the female gametophyte controls embryo and endosperm development. For the DEMETER (DME) gene, seed viability depends only on the maternal allele. DME encodes a large protein with DNA glycosylase and nuclear localization domains. DME is expressed primarily in the central cell of the female gametophyte, the progenitor of the endosperm. DME is...