The four major keratins of normal human epidermis (molecular mass 50, 56.5, 58, and 65-67 kD) can be subdivided on the basis of charge into two subfamilies (acidic 50-kD and 56.5-kD keratins vs. relatively basic 58-kD and 65-67-kD keratins) or subdivided on the basis of co-expression into two "pairs" (50-kD/58-kD keratin pair synthesized by basal cells vs. 56.5-kD/65-67-kD keratin pair expresse...

In this paper we describe a 66-kD protein that co-purifies with intermediate filaments from rat optic nerve and spinal cord but can be separated further by ion-exchange chromatography. This protein is distinct from the 68-kD neurofilament subunit protein as judged by isoelectric focusing, immunoblotting, peptide mapping, and tests of polymerization competence. This protein is avidly recognized ...

In previous work we found cytoplasmic dynein to be a complex of two catalytic heavy chains and at least seven co-purifying polypeptides of unknown function. The most prominent of these is a 74-kD electrophoretic species which can be resolved as two to three bands by SDS-PAGE. We have now selected a series of overlapping rat brain cDNAs encoding the 74-kD species. The deduced sequence of a full-...

The design rationale for many key distribution schemes for multicast networks are based on heuristic arguments on e ciency exi bility and scalability In most instances the choice of key server placement in a multicast network architecture is based on intuitive cryptographic considerations We use an analytical model of multicast group formation and network growth to look at the selection of a ke...

Crumbs homolog 3 (or Crumbs3, CRB3) is a polarity protein expressed by Sertoli and germ cells at the basal compartment in the seminiferous epithelium. CRB3 also expressed at the blood-testis barrier (BTB), co-localized with F-actin, TJ proteins occludin/ZO-1 and basal ES (ectoplasmic specialization) proteins N-cadherin/β-catenin at stages IV-VII only. The binding partners of CRB3 in the testis ...

BACKGROUND The pathogenesis of Kawasaki disease (KD) is commonly ascribed to an exaggerated immunologic response to an unidentified environmental or infectious trigger in susceptible children. A comprehensive framework linking epidemiological data and global distribution of KD has not yet been proposed. METHODS AND FINDINGS Patients with KD (n = 81) were enrolled within 6 weeks of diagnosis a...

This study builds a model to predict distribution coefficients (Kd) using the random forest (RF) method and machine learning based on Japan Atomic Energy Agency Sorption Database (JAEA-SDB). A database of ten input variables, including coefficient, pH, initial radionuclide concentrations, solid–liquid ratio, ionic strength, oxidation number, cation exchange capacity, surface area, electronegati...

A Surfels 3D reconstruction method based on improved KD-Tree is put forward, firstly collecting the discrete point cloud data through RGB-D camera, replacing the circular or oval surfel model with hexagonal model for modeling and determining the surfel radius in light of neighborhood distribution of sample points; Moreover, doing inside and outside relations test between one point model and ano...