25% of basal cell carcinoma (BCC) occurs in nose. The recently accepted treatment includes wide excision with safety margin 4 mm clinically normal skin. 3 major points the treatments are clearance, cosmetic and functional value. Often, due to its central location delicacy surrounding tissue makes it hard achieve standard surgical for lesions located size depth lesion may complicate therapy. The...

BACKGROUND The mechanisms behind microscopic colitis and exacerbations of ulcerative colitis are incompletely understood. It seems highly likely that both luminal antigens and bile are involved. The aim of this study was to test the hypothesis that bile acids increase colonic mucosal permeability by activating enteric neurones. METHOD The effect of 4 mM deoxycholic acid (DCA) on the appearanc...

BACKGROUND A common operation for cancer of the esophagus and cardia consists of transhiatal esophagectomy, proximal gastrectomy, and a cervical esophagogastric anastomosis. The oncologic adequacy of dividing the stomach 4 to 6 cm distal to palpable tumor is not well documented, and when a positive gastric margin is present on the final pathologic analysis, the appropriate management is not est...

We have assessed the proximal capsular extension of the ankle joint in 18 patients who had a contrast-enhanced MRI ankle arthrogram in order to delineate the capsular attachments. We noted consistent proximal capsular extensions anterior to the distal tibia and in the tibiofibular recess. The mean capsular extension anterior to the distal tibia was 9.6 mm (4.9 to 27.0) proximal to the anteroinf...

conclusions lv twist, torsion and untwist and also rate of them are significantly impaired in dcm and this impairment is well-related to lv global systolic and diastolic dysfunction. vvi is a new noninvasive technique that can be used to evaluate lv torsional parameters. results lv twist value (5.54 ± 1.94° in dcm vs. 11.5 ± 2.45° in control group) and also lv torsion (0.71 ± 0.28°/cm in dcm vs...

Diabetic cardiomyopathy (DCM) is a serious complication of diabetes. Hydrogen sulphide (H2S), a newly found gaseous signalling molecule, has an important role in many regulatory functions. The purpose of this study is to investigate the effects of exogenous H2S on autophagy and its possible mechanism in DCM induced by type II diabetes (T2DCM). In this study, we found that sodium hydrosulphide (...

INTRODUCTION Whipple's Pancreaticoduodenectomy has increasingly been used as an appropriate resectional procedure for tumors of the periampullary region which are pancreatic, periampullary, ampullary and biliary tumors. Our aim was to study the distribution and histopathologic features of these tumors and to examine local trends of periampullary neoplasms resected with a PD. METHODS A descrip...

OBJECTIVE In certain cases, the recurrent laryngeal nerve (RLN) has to be sacrificed. This often results in an inadequate length of residual RLN to be used in a reinnervation procedure. We investigated the length of the distal stump of the RLN from the inferior border of the inferior pharyngeal constrictor muscle (IPCM), where it is frequently compromised, to its entrance into the larynx. Our o...