Huntington's disease (HD) is a genetic neurodegenerative disorder characterized by motor, cognitive and psychiatric disturbances, and yet there is no disease-specific patient-reported health-related quality of life outcome measure for patients. Our aim was to develop and validate such an instrument, i.e. the Huntington's Disease health-related Quality of Life questionnaire (HDQoL), to capture t...

Introduction: Pulmonary involvement is the most common cause of mortality and disability in patients with systemic sclerosis and it significantly affects the quality of life in these patients. Therefore, early diagnosis and treatment of pulmonary involvement seems necessary in patients with SSc. In this study, we aimed to assess the health-related quality of life (HRQoL) in patients with Sclero...

background: polycystic ovary syndrome (pcos) has been shown to cause a reduction in health-related quality of life (hrqol). however, the relative degree of impairment in each domain differed among samples, and it was not clear which aspect of disease-specific hrqol (modified polycystic ovary syndrome health-related quality of life questionnaire) was most negatively affected. objective: to syste...

background: heart failure is a severe chronic disease and has a negative impact on the health-related quality of life (hrql). in addition to preventing disease progress, one of the important goals in heart failure treatment is to improve the patient’s quality of life. this study is aimed to compare three generic to specific quality of life instruments that are used in cardiac rehabilitation set...

quality of life in adolescent girls with diabetes hemmati maslakpak m[1]* received: 22 jun, 2012 accepted: 20 sep, 2012abstractbackground & aims: quality of life is now recognized as an important outcome for adolescents with diabetes. diabetes may affect men and women equally, but the suffering associated with the disease when it appears in adolescent girls will have disastrous effects on their...

b a c k g r o u n d & aim: quality-of-life (qol) among human immunodeficiency  virus (hiv)-infected people  has  been  the  center  of  focus  worldwide.  the  world  health  organization  qol  group (whoqol  group)  has developed  a 31-item qol questionnaire,  which  has been  translated  and used in many countries. this paper aimed at examining the reliability and validity of persian version ...

objective: oral health status particularly maxillofacial disorders in adolescents can affect different aspects of the quality of life. this study aimed to assess the age-related quality of life of students in two age groups of 11-14 years and 14-18 years to evaluate its correlation with orthodontic treatment need in adolescents in isfahan. methods: this cross-sectional study was conducted on 11...