During the course of experimental work on acquired hypotrichosis and canities, it was noted that in discoid lupus erythematosus of the scalp there was improvement of the inflammatory phase of the disease associated with calcium pantothenate therapy. Following this, a series of patients with subacute and localized and disseminated discoid lupus crythematosus was studied with oral calcium pantoth...

Discoid lupus erythematosus is the most common form of cutaneous lupus erythematosus. It is more common in women than in men, in individuals between 20 and 40 years of age. It is an inflammatory autoimmune disease in which genetically predisposed individuals are stimulated by hormonal and a variety of exogenous factors including UV radiation, stress, infections, and even temperature changes. Le...

Anti-DNA antibodies have been detected previously in patients with chronic discoid lupus erythematosus (DLE) despite the absence of overt systemic manifestations. 27 patients with DLE were followed up 3 years after the detection of anti-DNA antibodies in 7. None had developed other features of systemic lupus erythematosus. We conclude that the occasional finding of anti-DNA antibodies in patien...

Lupus erythematosus complex is an immune-mediated dermatological disease, mainly represented by the generalized and discoid forms. The last form described milder, as it limited to appearance of lesions, usually on face in mucocutaneous regions. Its pathophysiology considered multifactorial, however, continuous exposure ultraviolet radiation seems be very relevant trigger and/or worsen clinical ...

BACKGROUND Various kinds of alopecia can show small round or oval hairless patch. Dermoscopy could be a simple, useful tool for making a correct diagnosis. OBJECTIVE The aim of this study is to investigate clinical usefulness of dermoscopy for diseases with small round or oval hairless patch on the scalp. METHODS Dermoscopic examination was performed for 148 patients with small round or ova...