OBJECTIVE Autoimmune hemolytic anemia is characterized by the production of autoantibodies against erythrocyte membrane antigens. This study was carried out to identify the clinical, immunological and outcome characteristics of autoimmune hemolytic anemia patients treated at the (HC-UFMG) Pediatric Hematology Unit and the Hemocentro de Belo Horizonte. METHODS We evaluated 17 patients younger ...

An isolated IgA-mediated autoimmune hemolytic anemia can present a diagnostic challenge. When a routine direct antiglobulin test (DAT) is negative but clinical suspicion remains high, further testing with monospecific antisera should be performed. As with IgG-mediated WAIHA, steroids are first-line treatment, though splenectomy is often required to achieve a durable treatment response.

A 56-year-old Chinese lady with valvular heart disease and atrial fibrillation was referred to us from a private hospital for further management of autoimmune haemolytic anaemia. Physical examination and laboratory investigations did not support the diagnosis of haemolytic anaemia. However, direct antiglobulin test (DAT) was strongly positive with anti-IgG and negative with anti-C3d. There was ...

the most common form of acquired hemolytic anemia is associated with what appears to be autologous igg hemagglutinins. these anti-bodies may arise unexpectedly and in the absence of any recognizable underlying disease. however, they are observed not uncommonly as a complication of systemic lupus erythematosis, chronic lymphatic leukemia, lymphosarcoma, ulcerative colitis, etc. 'the red cells of...

A raised reticulocyte count is common in patients with immune or autoimmune haemolytic anaemia, and the result of the direct antiglobulin test (DAGT) is usually positive because of IgG or IgG and complement components on the red cells. We report on three patients who had low reticulocyte counts when they were most anaemic, and in whom no red cell autoantibodies could be detected by the DAGT. We...

S k a 1 k a B.: Hemolytic activity of Staphylococcus hyicus and Staphylococcus chromogenes. Acta vet. Bmo, 57, 1988: 3-11. Hemolytic activity of 135 ~ hyicus and 75 ~ chromogenes strains was examined on sheep, rabbit, human, horse and chicken blood agars. The agar bases were supplemented with 5 % washed erythrocytes of the corresponding animal species. The strains of both staphylococcal species...

Modification of the Microtiter reading mirror used in the standardized diagnostic complement fixation method permits convenient estimation of the results in per cent hemolysis by direct visual comparison with the hemolytic standards.

Twenty-nine lots of Bacti-Lab streptococci culture plates containing nalidixic acid, neomycin, and amphotericin B were inoculated with 25 strains of group A, B, C, F, and G strepotocci, 13 strains of nonstrepotcoccal organisms representative of the throat flora, and 198 fresh clinical thorat specimens to determine the accuracy of the plates in identifying group A streptococci. With the Bacti-La...

Autoimmune hemolytic anemia is a picture of hemolysis which is caused by autoantibodies against red blood cell surface antigens. It is classified as primary, secondary or warm and cold autoimmune hemolytic anemia according to the temperature at which antibodies react. It is usually an acute and self-limiting condition. Here, we present a three-year-old male patient who presented with malaise, p...