Background An Australian study including 4433 children found that delayed Diphtheria-Tetanus-acellular Pertussis–containing vaccination was associated with reduced risk of developing atopic dermatitis (AD) before age 1 year. Objective We assessed whether against diphtheria, tetanus, acellular pertussis, polio, and Haemophilus influenzae type b (Diphtheria, Tetanus, Pertussis – Inactivated Polio...

BACKGROUND An acellular Pertussis (aP) vaccine containing recombinant genetically detoxified Pertussis Toxin (PTgen), Filamentous Hemagglutinin (FHA) and Pertactin (PRN) has been developed by BioNet-Asia (BioNet). We present here the results of the first clinical study of this recombinant aP vaccine formulated alone or in combination with tetanus and diphtheria toxoids (TdaP). METHODS A phase...

Epidemiological data regarding tetanus and diphtheria immunity in elderly people in Brazil are scarce. During the First National Immunization Campaign for the Elderly in Brazil in April 1999, 98 individuals (median age: 84 years) received one tetanus-dyphtheria (Td) vaccine dose (Butantan Institute, lot number 9808079/G). Inclusion criteria were elderly individuals without a history of severe i...

OBJECTIVE The goal was to explore the association of being underinsured and receiving doses at a health department clinic (HDC) with not receiving all recommended adolescent vaccine doses. METHODS A total of 5657 adolescents, 13 to 17 years of age, were sampled in the National Immunization Survey-Teen in 2006-2007. RESULTS A total of 63.9% of all adolescents were covered by private health i...

sised the capacity of the immune system to respond effectively to numerous simultaneous antigens. Using data linkage, Miller et al found no evidence for an increase in admissions to hospital for serious bacterial infections following MMR vaccination. 9 One disadvantage of giving vaccines in combination is that it may not always be clear which component is responsible for a particular adverse ev...

introduction cephalic tetanus is a rare form of tetanus, defined as trismus and cranial nerve palsy. it has a mortality rate of 15 - 30%. case presentation the purpose of this case report was to present a case of cephalic tetanus with trismus, a rare form of tetanus, in an intravenous drug abuser. timely diagnosis and management prevented progression into the generalized form and made the patie...

Vietnam plans to replace the routine childhood diphtheria, pertussis and tetanus combination (DPT) vaccine with a pentavalent vaccine. The present study was performed to assess the immunogenicity and safety of the combined diphtheria, tetanus, whole-cell pertussis, hepatitis B (HepB), and Haemophilus influenzae type b (Hib) (DTwP-HepB-Hib) Quinvaxem® vaccine in children. A total of 131 infants ...

BACKGROUND The Indian state of Andhra Pradesh accounted for 50% diphtheria and 3% tetanus cases reported globally during 2005. During 2003-2006, there was a rising trend of diphtheria in Hyderabad, the state capital, whereas there was no major change in trend of tetanus cases. We estimated coverage of diphtheria and tetanus vaccine among children aged <or= 6 years and immunity against these dis...

background: immunization against diphtheria, tetanus and pertussis (dtp) has long been applied in iran using whole cell vac­cine. despite the role of whole cell dtp (dtwp) vaccine in reduction of mortality as a result of disastrous diseases such as diphtheria, tetanus, and pertussis, serious local and systemic complications have been attributed to these vaccines. this study was performed to det...

In 2005, two tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccines were licensed and recommended for use in adults and adolescents in the United States: ADACEL (sanofi pasteur, Swiftwater, Pennsylvania), which is licensed for use in persons aged 11--64 years, and BOOSTRIX (GlaxoSmithKline Biologicals, Rixensart, Belgium), which is licensed for use in persons aged 10...