Reaction of 6-amino-3-methyl-4-(substituted phenyl)-1,4- dihydropyrano[2,3-c]pyrazole-5-carbonitrile (1) with triethylorthoformate followed by treatment with hydrazine hydrate, formic acid, acetic acid, phenylisocyanate, ammonium thiocyanate and formamide afforded the corresponding pyranopyrimidine derivatives 2-6. Cyclocondensation of 1 with cyclohexanone afforded pyrazolopyranoquinoline 7. On...

p-dodecylbenzenesulfonic acid (dbsa) was used as a catalyst for a simple and efficient one-pot synthesis of aryl substititued tetrahydrobenzo[b]pyrans and dihydropyrano[c]chromens via initial knoevenagel, subsequent micheal and final heterocyclization reactions of aryl aldehyde, malononitrile and 4-hydroxycoumarin/dimedone in moderate to excellent yields. the present method was operationally si...

8 2 ABSTRACT 9 The reaction between m-diphenols (resorcinol, 2-methylresorcinol, 2,5-10 dimethylresorcinol, 3-methylphenol, orcinol, and phloroglucinol) and 2-alkenals (2-11 pentenal and 2-octenal) was studied in an attempt to understand the chemical pathways 12 involved in the scavenging ability of m-diphenols for the 2-alkenals produced as a 13 consequence of lipid oxidation. Phenols reacted ...

In our previous papers, we reported that isoflavones with a 3,3-dimethylallyl (prenyl) substituent at C-6, C-8 (ring A) or C-3' (ring B) were variously metabolized by the fungus Aspergillus flavus to give hydrates (luteone [1] and wighteone [2]), and deri­ vatives possessing dihydrofurano, dihydropyrano or 2,3-dihydrodihydroxyprenyl side-attachments (luteone [1], wighteone [2], 2,3-dehydrokievi...