BACKGROUND The ratio between the lengths of the second and fourth fingers (digit ratio: 2D : 4D), a purported negative correlate of prenatal androgen exposure, has been inversely related to age at menarche. However, a recent study found high digit ratios in carriers of a single variant in the LIN28B gene, which has been linked to delayed menarche. METHODS We investigated the association of di...

BACKGROUND We investigated the relationship between patterns of sex and hand differences in circadian wrist activity and digit ratio, a marker for prenatal androgen exposure. If the contribution of prenatal androgen exposure to sex differences in digit ratio underlies sex differences in circadian wrist activity, we predict that patterns of wrist activity will be correlated with digit ratio. M...

Males and females generally have different finger proportions. In males, digit 2 is shorter than digit 4, but in females digit 2 is the same length or longer than digit 4. The second- to fourth-digit (2D:4D) ratio correlates with numerous sexually dimorphic behavioral and physiological conditions. Although correlational studies suggest that digit ratios reflect prenatal exposure to androgen, th...

The ratio of second to fourth digit length (2D:4D) is a correlate of prenatal testosterone. High 2D:4D is associated with low prenatal testosterone, and reduced sensitivity to testosterone. Klinefelter's syndrome (KS; 47 XXY) affects the endocrine system, such that low testosterone levels are found in KS foetuses, new-borns and adults. To date, there are no published data regarding the pattern ...

Now advertized in at least one locale as the ‘sexy ratio’ with the caption, ‘Your hands give away your hotness’ (http://io9.com/ #!5794008; accessed 3 May 2011), an online summary of a recent study linking facial attractiveness to the ratio of the index and ring fingers indicates that digit ratio (2D:4D) research has reached mainstream culture. Digit ratio, most commonly the ratio of the index ...

In vertebrates, including humans, the relative length of the second to the fourth digit correlates with sex hormone-dependent behavioural, psychological and physiological traits. However, despite a decade of research, the underlying mechanism linking digit ratio to these sex hormone-dependent traits remains unclear. Previous work suggests that during embryo development, circulating levels of pl...

Sexual dimorphism in digit ration is related to genetic differences between species in response to prenatal exposure to hormones. In this study, the development of tetrapod digits, preliminary the ratio between the length of digit II and IV (2D: 4D) was investigated in 34 samples of Darevskia cholorogaster in the North of Iran. The results showed no significant differences between sexes in any ...