background trichoepithelioma is a rare benign skin lesion that originates from hair follicles. trichoepitheliomas are mostly seen in the scalp, nose, forehead, and upper lip. methods we present a large family of iranian origin with 15 individuals affected with multiple familial trichoepithelioma in four generations, and treated with three different methods. results trichoepithelioma is histolog...

dental caries, a progressive bacterial damage to teeth, is one of the most common diseases that affects 95% of the population and is still a major cause of tooth loss. unfortunately, there is currently no highly sensitive and specific clinical means for its detection in its early stages. the accurate detection of early caries in enamel would be of significant clinical value. since, it is possib...

kawasaki disease is a systemic vasculitis of children. among gastrointestinal symptoms of this disease jaundice occurs uncommonly. we present a 23 month boy with icter and clinical hepatitis and final diagnosis of kawasaki disease.

h.pylori infection stimulates immune responses. these responses at the mucosal level are predominantly of iga types, while circulating antibodies against this microorganism are predominantly igg classes. igm antibodies are rarely found and seem to be non-specific for this bacterium. in this research, water extract antigen, from three strains of h.pylori (isolated from patients with gastritis, d...

background :delay in diagnosis and treatment of acute appendicitis (aa) results in an increased rate of perforation, postoperative morbidity, mortality and hospital length of stay. several biochemical parameters including white blood cell (wbc) count, c-reactive protein (crp), interleukin-6 (il6) and procalcitonin (pct) have been used to further improve the clinical diagnosis of aa. the aim of ...

background gaucher’s disease (g.d.) is an autosomal recessive disorder resulting from the accumulation of glucocerebrosidase in the cells of macrophage-monocyte system as a result of a deficiency in lysosomal glucocerebrosidase. this enzyme is encoded by a gene on chromosome-1. here we report a case of gaucher’s disease .g.d is rare in yazd. case reports we reported a patient that presented wit...

abstract background thalassemia is common in the iranian population, and it must be considered in the differential diagnosis of the microcytic hypochromic anemia. the molecular analysis of β-thalassemia is necessary for prenatal molecular diagnosis. α-thalassemia caused by loss of function of either one of the two duplicated α-globin genes or in less frequent non deletion mutations mostly locat...

conclusions igm alone is not a marker for viral shedding in genital tract. molecular testing in conjunction of igg test should be evaluated as an option to determine hsv status, and applied for research on hsv genital infections records. methods two hundred and eight females were included in the study; igm antibodies against hsv1/2 were detected in serum samples; the real-time polymerase chain ...