Coccidiostats are synthetic drugs administered to animals, especially to poultry, to cure coccidiosis. In this paper, we present a selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to analyze residues of five synthetic coccidiostats in eggs: clazuril, diclazuril, robenidine, nicarbazin, toltrazuril and its two metabolites. The extraction efficiency was evaluated by test...

The purpose of the research is to determine efficiency coccidiostat combined with probiotic for treatment coccidiosis in rabbits a comparative aspect. Materials and methods . Rabbits suffering from eimeriosis were treated probiotic. anticoccidial drug benzeneacetonitrile group, Diclacox 2.5%, active ingredient which diclazuril, Mucinolextra, freeze-dehydrated biomass Bifidobacterium globosum, E...

A simple stability-indicating high-performance liquid chromatographic method was developed and validated for the determination of diclazuril (DIC) in the presence of its induced degradation products. The drug was subjected to stress stability study including acidic, alkaline, photolytic, thermal and oxidative stress conditions, and the stressed samples were analyzed by the proposed method. The ...