Objective: To describe the toxicity of deliberate guanidine thiocyanate ingestion and it's treatment including dialysis. Case report: A 52-year-old male presented to hospital with abdominal pain after giving a history of ingesting bottled water. His initial vital signs and examination were normal. Soon after the patient became confused and agitated, necessitating intubation and ventilation for ...

This paper presents the development of water-permeable dialysis membranes that are suitable for an implantable microdialysis system that does not use dialysis fluid. We developed a microdialysis system integrating microfluidic channels and nanoporous filtering membranes made of polyethersulfone (PES), aiming at a fully implantable system that drastically improves the quality of life of patients...

During peritoneal dialysis solutes and water are transported across the peritoneum, a thin “membrane” lining the abdominal and pelvic cavities. Dialysis fluid containing an “osmotic agent”, usually glucose, is infused into the peritoneal space, and solutes and water pass from the blood into the dialysate (and vice versa). The complex physiological mechanisms of fluid and solute transport betwee...

Studies were conducted on the microbiological quality of fluids associated with different types of dialysis systems located in six dialysis centers and 14 homes. Included were (i) single-pass systems employing either parallel flow (Kiil or Gambro) or capillary cartridge dialyzers and (ii) recirculating single-pass and batch recirculating systems using coil dialyzers. Microbiological assays were...

Control of osmolarity, as well as sodium, urea, and water balance in anuric patients under intermittent haemodialysis therapy is fundamentally different from subjects with normal kidney function. Whereas in subjects with normal kidney function excretion of solutes and water is performed continuously, during dialysis, within a short period of time most sodium and only a small amount of urea are ...

METHODS The present report attempts to illustrate the positive impact on the microbiological quality of dialysis patients over a 15-year period through the progressive implementation of state-of-the-art technological strategies and the optimization of microbiological surveillance procedures in five dialysis units in Sardinia. RESULTS Following on better microbiological, quality controls of di...

SIR, Patients with kidney fai lure who are on maintenance hemodialysis are more frequently at risk of opportunistic fungal infections. Infection is the most common cause of death in patients with acute kidney failure.1,2 These patients have also limited urinary excretion that makes them susceptible to infectious diseases. One of the major causes of morbidity and mortality in patients undergoing...

Originally a definition of water quality for the semiconductor industry, the term ‘ultrapure’ has been adopted by the dialysis community. The discussion has developed from basic definitions and methods for quantification to clinical benefits and recommendations for implementation. Today, ultrapure dialysis fluid is subject to the demands of evidence-based medicine or at least evidence-based cos...

Wearable artificial kidney (WAK) has been considered an alternative to standard hemodialysis (HD) for many years. Although various novel WAK systems have been recently developed for use in clinical applications, the target performance or standard dose of dialysis has not yet been determined. To calculate the appropriate clearance for a HD-based WAK system for the treatment of patients with end-...