Isolated soy-protein products are useful for food ingredients because they provide solubility, water binding, fat adsorption, emulsification, viscosity, gelation, foaming, adhesion and cohesion, texturization, and flavor formation. Soy-protein concentrates (SPCs) and soy (SPIs) are the representative soy Conventionally, SPCs and SPIs have been produced by removing non-protein portions such as o...

The manufacturing of bispecific antibodies can be challenging for a variety of reasons. For example, protein expression problems, stability issues, or the use of non-standard approaches for manufacturing can result in poor yield or poor facility fit. In this paper, we demonstrate the use of standard antibody platforms for large-scale manufacturing of bispecific IgG1 by controlled Fab-arm exchan...

In this paper, we deal with the model-based time-optimal operation of a batch diafiltration process in the presence of membrane fouling. Membrane fouling poses one of the major problems in the field of membrane processes. We model the fouling behavior and estimate its parameters using various methods. Least-squares, least-squares with a moving horizon, recursive least-squares methods and the ex...

Membrane diafiltration process was developed in order to fractionate the water soluble proteins of supernatant obtained after Spirulina bead milling disruption and centrifugation. The crude extract filtered with 50 kDa, 150 300 kDa or 0.2 µm membranes. Phycocyanin purified extracts were produced filtration on membrane allowed high recovery (more than 89%) A C into retentate permeate as well sep...