Cardiomyopathies are an important and heterogeneous group of diseases. The awareness and knowledge of these diseases in both the public and medical communities historically has been impaired by persistent confusion surrounding definitions and nomenclature. Classification schemes, of which there have been many, (Thiene et al., 2000, 2004; Richardson et al., 1996) are potentially useful in drawin...

Cardiomyopathies can generally be categorized into two groups, based on World Health Organization guidelines: extrinsic and intrinsic. In extrinsic cardiomyopathies the primary pathology is outside the myocardium. Most cardiomyopathies are extrinsic, because the most common cause is ischemia. Intrinsic cardiomyopathies is weakness in the muscle of the heart that is not due to an identifiable ex...

conclusions these findings emphasize the potential clinical benefits of therapeutic procedures such as cardiac resynchronization therapy (crt) or apex-sparing volume-reduction surgery in dcm. a better definition of the role and implications of reverse apical torsion in dcm and its importance and effectiveness in making therapeutic decisions like crt implantation requires further studies. case p...

The definition and classification of the cardiomyopathies has been traditionally a complex and quite variable subject. In 2006, the American Heart Association issued a scientific statement elaborated by a task force of experts that contemplated the important development of molecular genetics in recent years, to explain the etiology of the diseases of cardiac muscle, or cardiomyopathies, previou...

Cardiomyopathies constitute a heterogeneous group of diseases with varying etiologies and clinical presentation. Advances in genetic testing have made it possible to establish genotype-phenotype relationships, determine prognosis, choose specific treatments the pediatric population. Therefore, objective this review is assist reasoning underscore importance etiological diagnosis different diseas...

Examples of toxic cardiomyopathies of various characteristics are presented. Daunomycin and doxorubicin, antineoplastic drugs, cause multifocal cardiomyopathies and intractable heart failure by cardiotoxic mechanisms; these effects are delayed and related to the cumulative dose. Cobalt caused diffuse vacuolar cardiomyopathy in chronic beer drinkers. The development of fulminant heart failure wa...

Mitochondria are found in all nucleated human cells and perform various essential functions, including the generation of cellular energy. Mitochondria are under dual genome control. Only a small fraction of their proteins are encoded by mitochondrial DNA (mtDNA), whereas more than 99% of them are encoded by nuclear DNA (nDNA). Mutations in mtDNA or mitochondria-related nDNA genes result in mito...