ca1 region of hippocampus has an important role in learning and memory. previous reports have shown that androgens like testosterone and its metabolites are present in high concentration in ca1 region of hippocampus. androgen receptors have also high density in this region. therefore, it is suggested that neurohormones in ca1 have an important role in learning and memory. it is likely that test...

BACKGROUND The conjugation of gold nanoparticles with biocides such as natural products, oligosaccharides, DNA, proteins has attracted great attention of scientists recently. Gold NPs covered with biologically important molecules showed significant enhancement in biological activity in comparison with the activity of the free biocides. However, these reports are not very systematic and do not a...

     CA1 region of hippocampus has an important role in learning and memory. Previous reports have shown that androgens like testosterone and its metabolites are present in high concentration in CA1 region of hippocampus. Androgen receptors have also high density in this region. Therefore, it is suggested that neurohormones in CA1 have an important role in learning and memory. It is likely that...

BACKGROUND Dihydrotestosterone (DHT) induces androgenic alopecia by shortening the hair follicle growth phase, resulting in hair loss. We previously demonstrated how changes in the microRNA (miRNA) expression profile influenced DHT-mediated cell death, cell cycle arrest, cell viability, the generation of reactive oxygen species (ROS), and senescence. Protective effects against DHT have not, how...

of the 3H-label in their experiments is associated with the cells is difficult to interpret. Although some of the experiments by Hammes et al. are consistent with their “bound steroid” hypothesis (see, for example, Figure 2A), others are not (for example, see Figures 2B and 2C). At a concentration of 1 nM DHT plus 1 nM SHBG, 50% of the steroid exists in the free form. One nanomole of DHTSHBG an...

The recent proliferation of decentralized distributed hash table (DHT) proposals suggests a need for DHT benchmarks, both to compare existing implementations and to guide future innovation. We argue that a DHT-based query engine provides a unified framework for describing workloads and faultloads, injecting them into a DHT, and recording and analyzing the observed system behavior. To illustrate...

This paper investigates the development of a DHT-based storage engine for a database management system (DBMS). The storage engine is responsible for implementing the interface between an SQL query processor and a DHT, by translating operations based on relations to DHT standard operations. By combining DHTs to DBMSs we achieve scalability, decentralization, and fault tolerance, due to a DHT-bas...

Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in women of reproductive age, with a prevalence of 5-8%. Type 2 diabetes and cardiovascular disease (CVD) are its long-term complications. Targeted therapies addressing both these complications together are lacking. Glucagon like peptide-1 (GLP-1) agonists that are used to treat type 2 diabetes mellitus have beneficial eff...

As an append-only distributed database, blockchain is utilized in a vast variety of applications including the cryptocurrency and Internet-of-Things (IoT). The existing solutions show downsides communication storage scalability, as well decentralization. In this article, we propose LightChain, which first architecture that operates over Distributed Hash Table (DHT) participating peers. LightCha...

The androgen receptor (AR) mediates the growth of benign and malignant prostate in response to dihydrotestosterone (DHT). In patients undergoing androgen deprivation therapy for prostate cancer, AR drives prostate cancer growth despite low circulating levels of testicular androgen and normal levels of adrenal androgen. In this report, we demonstrate the extent of AR transactivation in the prese...