Subverting runtime data flow is common in many current software attacks. Data Flow Integrity (DFI) is a policy whose satisfaction can prevent such attacks. This paper develops a formal foundation on DFI specification, and characteristics of its enforcement techniques with formulations of hypotheses and guarantees. Enforcement techniques are based on static analysis and program monitoring at run...

BACKGROUND Varicocele is associated with high levels of DNA damage in spermatozoa due to oxidative stress and elevated levels of sperm DNA fragmentation, which has been currently proposed to be an essential additional diagnostic test to be recommended for patients with clinical varicocele. The aim of this study was to evaluate the parameters of semen and the DNA fragmentation index (DFI) in pat...

We have demonstrated displacementand frequency-noise-free laser interferometry (DFI) by partially implementing a recently proposed optical configuration using bidirectional Mach-Zehnder interferometers (MZIs). This partial implementation, the minimum necessary to be called DFI, has confirmed the essential feature of DFI: the combination of two MZI signals can be carried out in a way that cancel...

PURPOSE It is not known whether childhood cancer and its treatment are associated with sperm DNA damage, which subsequently affects fertility and might be transmitted to the offspring. The aim of this study is to assess DNA fragmentation index (DFI) as an indicator of sperm DNA integrity in childhood cancer survivors (CCS), with treatment regimen taken into account. EXPERIMENTAL DESIGN In 99 ...

Decisive heifer management for improved lactation and reduced dystocia requires a systematic analysis of age, body weight (BW), and average daily gain (ADG) using an adequately large sample size. The objective of this study was to determine effects of BW and age at first breeding and ADG until pregnancy on yields of milk, milk fat, and milk protein in the first lactation and the occurrence of d...

BACKGROUND Diabetes is a major risk factor for skin and skin structure infection (SSSI), and the global burden of diabetics with SSSI is enormous. The more complex microbiology of diabetic foot infection (DFI) is well established, but it is not known whether microbiological etiology differs between diabetics and nondiabetics in other disease entities under the umbrella of complicated SSSI (cSSS...

STUDY QUESTION Does the sperm DNA fragmentation index (DFI) improve depending on the FSH receptor (FSHR) genotype as assessed by the nonsynonymous polymorphisms rs6166 (p.N680S) after 3 months of recombinant FSH treatment in men with idiopathic infertility? SUMMARY ANSWER FSH treatment significantly improves sperm DFI only in idiopathic infertile men with the p.N680S homozygous N FSHR. WHAT...

Aim: To investigate the prevalence of high levels of sperm DNA damage among men from infertile couples with both normal and abnormal standard semen parameters. Methods: A total of 350 men from infertile couples were assessed. Standard semen analysis and sperm chromatin structure assay (SCSA) were carried out. Results: Ninety-seven men (28% of the whole study group) had a DNA fragmentation index...

BACKGROUND The sperm chromatin structure assay (SCSA) has been suggested as a predictor of fertility in vivo as well as in vitro. The available data however, have been based on limited numbers of treatments. We aimed to define the clinical role of SCSA in assisted reproduction. METHODS A total of 998 cycles [387 intrauterine insemination (IUI), 388 IVF and 223 ICSI] from 637 couples were incl...