Serum containing dextrans of average molecular weight 40,000 (“Dextran-40”), 70,000 (“Dextran-70”), or 75,000 (“Dextran-75”) become turbid when biuret reagent is added (1, ). This interference has been overcome (3) by first precipitating serum proteins with trichioroacetic acid before applying the biuret reaction. Positive interference of these drugs with the o-toluidine glucose assay has also ...

The extracellular dextrans produced from sucrose by Streptococcus mutans strains BHT and GS-5 did not prevent the synthesis or release of active bacteriocins by these two strains. In addition, several streptococci that were genetically sensitive to these bacteriocins, and that could synthesize a variety of extracellular dextrans and levans from sucrose, remained phenotypically sensitive when gr...

Many extensive studies have been made on the glucose polymers, known as dextrans, whichare produced from sucrose by the transglucosidase activity of species in the genus Leucomostoc. Less work has been described, however, on similar polysaccharides produced from sucrose by streptococcal species. Niven, Smiley & Sherman (1941) reported that various strains of Streptococcus bovis, of unrecorded o...

Novel (S)-camptothecin-dextran polymers were obtained by "click" grafting of azide-modified (S)-camptothecin and alkyne-modified dextrans. Two series based on 10 kDa and 70 kDa dextrans were prepared with a degree of substitution of (S)-camptothecin between 3.1 and 10.2%. The binding properties with β-cyclodextrin and β-cyclodextrin polymers were measured by isothermal titration calorimetry and...

We studied the effectiveness with which various charcoal preparations separate free [3H]pteroylglutamate from that complexed with milk folate binder. We tested, in various concentrations, uncoated charcoals and charcoals coated with dextrans of various molecular weights, or with albumin, hemoglubin, or polyvinylpyrrolidone with an average molecular weight of 40 000. Althouth there was some dist...

Dextrans modified with alkyne and azide groups through hydrolysable carbonate esters form degradable microcapsules after Cu(I) catalysed 'click' reaction between azides and alkynes yielding triazole cross-links.