Exploration of design spaces is an important step in decision-based design. In consumer product development, precise design specifications are not known at the beginning of the design process. It is usually design team’s responsibility to find out the specifications as a part of the design process. This results in large design spaces in consumer product development. Furthermore, market window i...

The advance in the global environment, rapidly changing markets, and information technology has created a new stage for design. In such an environment, one strategy for success is the Collaborative Product Development (CPD). Organizing people effectively is the goal of Collaborative Product Development, and it solves the problem with certain foreseeability. The development group activities are ...

As two recent trends in Web development, Widgets and mashups, are converging, we claim that there is a growing need to define a Widget Space configuration language to allow building flexible personal learning environments that could be independent of a runtime environment. By integrating the do-it-yourself dimension of a Web portal or Web mashup and the social dimension of the Web, we describe ...

This article presents a rule–based agent mechanism as the kernel of a ubiquitous end–user, UI–independent programming system. The underlying goal of our work is to allow end–users to control and program their environments in a uniform, application–independent way. The heterogeneity of environments, users and programming skills, as well as the coexistence of different users and domains of automa...

Using a microchannel assay, we demonstrate that cells adopt distinct signaling strategies to modulate cell migration in different physical microenvironments. We studied α4β1 integrin-mediated signaling, which regulates cell migration pertinent to embryonic development, leukocyte trafficking, and melanoma invasion. We show that α4β1 integrin promotes cell migration through both unconfined and co...

statement of problem: nowadays, evaluation of the development of occlusion in deciduous teeth for creating corrective occlusion in permanent teeth is one of the most important objectives of pediatric dentistry. in other countries, a vast number of researches have been accomplished on the details of occlusion in deciduous teeth. but, unfortunately, there is still no accurate information about th...

The increasing rate of urbanization and rate of population growth over the 20th century has led to various problems such as traffic congestion, air pollution, and lack of open and green spaces that have affected the cities and their citizen's life. This condition has led to increasing demands for more land use, homes, and work places, more public transport and mass transit systems and modern in...