نتایج جستجو برای: desaturation
تعداد نتایج: 3472 فیلتر نتایج به سال:
RATIONALE Obesity increases the risk and severity of sleep-disordered breathing. The degree to which excess body weight contributes to blood oxygen desaturation during hypopneic and apneic events has not been comprehensively characterized. OBJECTIVES To quantify the association between excess body weight and oxygen desaturation during sleep-disordered breathing. METHODS A total of 750 adult...
BACKGROUND Synthesis of polyunsaturated fatty acids (PUFAs) in the endoplasmic reticulum of plants typically involves the fatty acid desaturases FAD2 and FAD3, which use cytochrome b(5) (Cb5) as an electron donor. Higher plants are reported to have multiple isoforms of Cb5, in contrast to a single Cb5 in mammals and yeast. Despite the wealth of information available on the roles of FAD2 and FAD...
BACKGROUND AND AIMS The clinical impact of nocturnal desaturation on health related quality of life (HRQL) and sleep in chronic obstructive pulmonary disease (COPD) has been little studied. The aim of this study was to evaluate the prevalence and clinical impact of nocturnal desaturation in a typical outpatient population with COPD. PATIENTS AND METHODS Between 2002 and 2005, consecutive pati...
The sterol regulatory element-binding proteins (SREBP) are key transcriptional regulators of lipid metabolism and cellular growth. It has been proposed that SREBP signaling regulates cellular growth through its ability to drive lipid biosynthesis. Unexpectedly, we find that loss of SREBP activity inhibits cancer cell growth and viability by uncoupling fatty acid synthesis from desaturation. Int...
Oxygen desaturation during sleep in patients with cystic fibrosis has been attributed to changes in the end-expiratory volume during rapid eye movement (REM) sleep, leading to worsening of the ventilation-perfusion distribution. The purpose of this study was to describe the changes in ventilation during sleep that may contribute to the oxygen desaturation. Six adolescent males with moderate to ...
Molecular dynamics simulations were conducted to evaluate the effect of water desaturation on ion and density distributions diffusion properties in a clay mineral mesopore. Simulations carried out using polarizable model (PIM) force field. Desaturation pore was responsible for significant changes localization mobility molecules ions, especially most unsaturated conditions, which charge overcomp...
OBJECTIVE Infants who sleep prone and face down on soft bedding are particularly vulnerable for sudden infant death syndrome. It has been suggested that 1 mechanism of death in this situation involves rebreathing of expired air. Many infants tolerate rebreathing while lying prone face down for long periods with stable saturations. Others occasionally have rapid desaturations and may require int...
In the application of vehicle power supply and distributed power generation, there are strict requirements for the pulse width modulation (PWM) converter regarding power density and reliability. When compared with the conventional insulated gate bipolar transistor (IGBT) module, the Reverse Conducting-Insulated Gate Bipolar Transistor (RC-IGBT) with the same package has a lower thermal resistan...
Desaturation of [1-r4C]stearic acid, [lJ4C]palmitic acid, and [l-14C]stearoyl-CoA was measured in homogenates of lo-day-old rat brain. Desaturation was maximal with stearoyl-CoA at pH 6.0 to 6.6. With free fatty acids, monoene formation was maximal at pH 7.2 to 7.6; stearic acid was more actively desaturated than palmitic acid. Activity with stearic acid or stearoyl-CoA was linear with protein ...
Background: With the goal of optimizing tissue perfusion and maintaining adequate oxygen delivery, nurses play an important role in monitoring oxygenation and ventilation. Nursing practices may affect oxygen saturation in critically ill patients. Aim of study was to determine the relationship between nursing practices and oxygen desaturation in critically ill patients. Design: A descriptive res...
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