CONTEXT AND OBJECTIVE The technique of obtaining human skin with dermis and epidermis reconstructed from cells isolated from patients can enable autologous skin grafting on patients with few donor sites. It also enables in vitro trials on chemicals and drugs. The objective of this work was to demonstrate a method for obtaining human skin composed of associated dermis and epidermis, reconstructe...

The embryonic origin of the dermis in vertebrates can be traced back to the dermomyotome of the somites, the lateral plate mesoderm and the neural crest. The dermal precursors directly overlying the neural tube display a unique dense arrangement and are the first to induce skin appendage formation in vertebrate embryos. These dermal precursor cells have been shown to derive from the dorsomedial...

Reactive oxygen species play an important role in inflammatory skin diseases such as psoriasis. Reactive oxygen species synthesis is catalysed by iron and some species are scavenged by ascorbic acid. The aim of this work was to assess iron and ascorbic acid in uninvolved and involved psoriatic dermis and to compare the corresponding concentrations in the dermis of healthy subjects. Microdialysi...

Table 1. Types of materials used in pelvic organ prolapse repair (5,7,8,9). A. Biologics: 1Autologous fascia: Rectus fascia, fascia lata, vaginal mucosa, skin graft 2Heterologous: i) Allogenic: CadavaericDura matter, Rectus sheath, Fascia lata, Dermis, ii) Xenogenic: Porcine dermis, small intestine submucosa, bovine pericardium, fetal bovine dermis. B. Synthetics: 1Absorbable: Polyglycolic acid...