نتایج جستجو برای: derived stem cells

تعداد نتایج: 1862571  

Vosough, Massoud, Zahmatkesh, Ensieh,

Pluripotent stem cells (PSCs) may be offered as an unlimited cell source for the hepatocyte generation. The generation of hepatocytes from stem cells in vitro would provide an alternative cell source for applications in drug discovery and cell transplantation. In this review, we discuss different approaches to generate pluripotent stem cell-derived hepatocytes, advantages, limitations for each ...

Journal: :iranian journal of basic medical sciences 0
mohamadreza baghaban eslaminejad department of stem cell and developmental biology, royan institute for stem cell biology and technology, iranian academic center for education, culture and research (acecr), tehran, iran soura mardpour department of developmental biology, university of science and culture, tehran, iran marzieh ebrahimi department of stem cell and developmental biology, royan institute for stem cell biology and technology, iranian academic center for education, culture and research (acecr), tehran, iran

objective(s) some investigation has indicated that adipose-derived stem cells possess different surface epitopes and differentiation potential according to the localization of fat pad from which the cells were derived. in the present study proliferation capacity and aging of such cells were explored. materials and methods adherent cells were isolated from the collagenase digests of adipose tiss...

Mahdieh Sadat Ghiasi, Mohsen Sheykhhasan,

The cartilage is a connective tissue that, due to the strength of its extracellular matrix, allows the tissue to tolerate mechanical stress without undergoing permanent deformation. It is responsible for the support of soft tissues and due to its smooth surface and elasticity, gives the joints the ability to slip and bend. excessive weight, excessive activity, or trauma can all cause cartilage ...

Journal: :research in molecular medicine 0
hatef ghasemi hamidabadi department of anatomy & cell biology, faculty of medicine, mazandaran university of medical sciences, sari, iran nourollah rezaei department of anatomy & cell biology, faculty of medicine, mazandaran university of medical sciences, sari, iran reza mahmoudi cellular and molecular research center, yasuj university of medical sciences, yasuj, iran maryam nazm bojnordi department of anatomy and cell biology, faculty of medicine, mazandaran university of medical sciences, sari, iran.

background: as condition and component of culture determine fate map of spermatogonial stem cells (sscs), the aim of this study was to evaluate of growth factors gdnf, lif and ra on proliferation and differentiation of ssc. materials and methods: sscs were cultured in two groups: the first group gdnf and lif and the second group ra. the number of clumps and colony formation was monitored during...

Journal: :modares journal of medical sciences: pathobiology 2011
fatemeh zolghadr majid sadeghizadeh naser amirizadeh mehrdad behmanesh saman hosseinkhani

objective: evaluating the effects of p-benzoquinone and hydroquinone on the runx2 expression and osteoblastic differentiation of human marrow derived mesenchymal stem cells (mscs). materials and methods: bone marrow mscs obtained by cultivating marrow mononuclear cells, were exposed to 10μm of either p-benzoquinone or hydroquinone. following chemical treatment, runx2 gene expression was assess...

Journal: :iranian journal of veterinary medicine 2013
mahdieh rezaei shahram jamshidi anna saffarpour mahdi ashouri davood sharifi

background: stem cell therapy in small animal medicineis still in its infancy and few in vitro and in vivo research projectsregarding animal mesenchymal stem cells (mscs) have beencarried out. on the other hand, cell tracking is the first step of thecell-based therapies and is essential to recognize cell fate posttransplantation. objectives: the aim of this study was toisolate, characterize, an...

Journal: :international journal of reproductive biomedicine 0
seyyed mohammad reza hashemnia somayeh atari-hajipirloo shiva roshan- milani nasim valizadeh sonya mahabadi fatemeh kheradmand

background: the anticancer agent imatinib (im) is a small molecular analog ofatp that inhibits tyrosine kinase activity of platelet derived growth factors (pdgfs)and stem cell factor (scf) receptor in cancer cells. however these factors have a keyrole in regulating growth and development of normal sertoli, leydig and germcells.objective: the aim of this study was to determine cell viability, pd...

بهاروند, حسین, مرادی , شریف ,

Embryonic stem cells are pluripotent stem cells which have the ability to indefinitely self-renew and differentiate into all differentiated cells of the body. Regarding their two main properties (unlimited self-renewal and multi-lineage differentiation), these cells have various biomedical applications in basic research and cell based therapy. Because the transplantation of differentiated cells...

Arm grooves of star-fish have mesenchymal stem cells derived from adipose tissue cell. Widespread studies have shown that stem cells derived from adipose-derived mesenchymal stem cell from bone marrow have many similarities in terms of the ability to differentiate into a variety of tissues. Most of the animals live in warm and shallow waters and the waters of this feature is that it is low in d...

حسینی برشنه, علی, رودبارانی, رضا, سلطانی, دانش, مدرسی, محمد حسین,

Stem cells are undifferentiated and multi pluripotent cells which can differentiate into a variety of mature cells and tissues such as nervous tissue, muscle tissue, epithelial tissue, skeletal tissue and etc. Stem cells from all different source have three unique features: 1) Proliferative capability: Stem cells are capable of self dividing and self renewing for long periods or more than six m...

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