نتایج جستجو برای: derived growth factor α

تعداد نتایج: 1974380  

Background and Objectives: Different diets have important roles in human health and aging. In the current study, we aimed to characterize the Klotho, an anti-aging protein, gene expression and protein level in the serum and assess the protein levels of Transforming growth factor-β and Platelet-derived growth factor in old rats which treated with different diets (high-fat, high-protein, low calo...

اطلسی, محمدعلی, خانلرخانی, ندا, راگردی کاشانی, ایرج, طاهریان, علی‌اکبر, نادریان, همایون, نیکزاد, حسین,

Background: Adipose-derived stem cells (ADSCs) have noticeable self-renewal ability and can differentiate into several cell lines such as adipocytes, osteoblasts, chondrocytes, and myocytes. Progesterone plays a significant role in the myelination of peripheral nerves. Regarding the role of progesterone on the myelination of peripheral nervous system, we evaluated its effect...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2007
Teresa Guida Suresh Anaganti Livia Provitera Richard Gedrich Elizabeth Sullivan Scott M Wilhelm Massimo Santoro Francesca Carlomagno

PURPOSE Targeting of KIT and platelet-derived growth factor receptor (PDGFR) tyrosine kinases by imatinib is an effective anticancer strategy. However, mutations of the gatekeeper residue (T670 in KIT and T681 in PDGFRbeta) render the two kinases resistant to imatinib. The aim of this study was to evaluate whether sorafenib (BAY 43-9006), a multitargeted ATP-competitive inhibitor of KIT and PDG...

Journal: :Journal of Biological Chemistry 2005

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