the aim of this study was to develop a derivative of chitosan as pharmaceutical excipient used in sustained-release matrix tablets of poorly soluble drugs. a water-soluble quaternary ammonium carboxymethylchitosan was synthesized by a two-step reaction with carboxymethylchitosan (cmcts), decylalkyl dimethyl ammonium and epichlorohydrin. the elemental analysis showed that the target product with...

The matrix exponential is a much-studied matrix function having many applications. The Fréchet derivative of the matrix exponential describes the first-order sensitivity of eA to perturbations in A and its norm determines a condition number for eA. Among the numerous methods for computing eA the scaling and squaring method is the most widely used. We show that the implementation of the method i...

Following a review of periodontal wound healing, this article discusses techniques designed to optimise including guided-tissue regeneration and using enamel matrix derivatives. Enamel derivatives are porcine derived, thought stimulate differentiation, proliferation, migration mineralization in cells found tissues. This charts the development surgical outcomes from regenerative techniques, addi...

Various periodontal plastic surgical techniques are employed in obtaining root coverage. Recently, the use of an enamel matrix derivative (EMD) has been reported in such treatment. We report 2 cases of root coverage surgery with a coronally positioned flap in combination with EMD (CPF+EMD) and connective tissue graft in combination with EMD (CTG+EMD). Case 1: The patient was a 25-year-old woman...

In this paper, state-derivative and especially output-derivative feedbacks for linear time-invariant systems are derived using control approach similar to linear quadratic regulator (LQR). The optimal feedback gain matrices are derived for the desired performance. This problem is always solvable for any controllable system if the open-loop system matrix is nonsingular. Explicit expression of th...

Wediscuss how to generalize the concept of vector derivative tomatrix derivative, propose two definitions, a ‘broad’ and a ‘narrow’ one, compare the two definitions, and argue in favor of the narrow definition. © 2010 Elsevier Inc. All rights reserved.

Background—Periodontal disease results in the loss of the attachment apparatus. In the last three decades, an increasing effort has been placed on seeking procedures and materials to promote the regeneration of this tissue. The aim of this paper is to evaluate the effect of enamel matrix derivative (EMD) during regenerative procedures. In addition, a meta-analysis is presented regarding the cli...