abstract background beta-thalassemia is a common hereditary hemoglobinopathy, which is a reason of microcytic hypochromic anemia. patients with major thalassemia require multiple blood transfusions. this study evaluated growth in thalassemic patient and relationship with ferritin level. materials and methods this is a cross sectional study on seventy patients (36 boys, 34girls) with transfusion...

background: major -thalassemia is the most common monogenic known disorder in iran and about 15000 persons are af fected. the purpose of this study was to evaluate the prevalence of orofacial complications. methods: in this cross-sectional study during 2003-2004, 300 patients with major -thalassemia referring to 8 hospitals for routine examinations, blood infusion and treatment in cities of teh...

introduction: there have been many reports and papers on deficient, normal and high levels of copper in patients with thalassemia major. the aim of this study is to evaluate copper status in a series of more than 300 patients with thalassemia major and determine the degree of copper deficiency or excess. methods: three hundred and seventy patients with thalassemia major over 5 years of age were...

background there are different and controversial reports about zinc deficiency in patients with major thalassemia. objectives the aim of this study was to evaluate zinc status in patients with major thalassemia in sistan and baluchistan province, southeastern iran. patients and methods the study was performed in ali asghar hospital, a specialized governmental hospital located in zahedan, iran. ...

Advances in treatment of thalassemia have led to the aging of thalassemic patients, and consequently concern about successful reproductive outcome is augmented. Although women with thalassemia intermedia only were considered competent of achieving pregnancy, case series reveal the willingness of both thalassemia major and thalassemia intermedia women to have a family. Pregnancy in general is ch...

Thalassemia is a heterogeneous group of genetic disorder with the defective synthesis one or more globin chains. β-thalassemia global disease high prevalence in Africa, Southeast Asia and Mediterranean countries. In Malaysia, α are commonest. articles that we reviewed, transfusion-dependent highly associated complications related to thalassemia such as cardiovascular disease, endocrine disorder...

Background: Thalassemia is one of the common inherited blood disorders and Beta Major a homozygous form deficiency beta globin chain synthesis causing severe transfusion-dependent anemia, manifesting between 6 24 months life. Objectives: The objective study to pattern cardiac function in children adolescents with beta-thalassemia major by 2D Echocardiography its correlation serum ferritin level...

Background Thalassemia is a common inherited hemoglobin disorder caused by deficiency of one or more globin subunits. Substitution variants and deletions in the HBB gene are major causes β-thalassemia, which large fragment rare difficult to be detected conventional polymerase chain reaction (PCR)-based methods. Case report In this study, we reported 26-year-old Han Chinese man, whose routine bl...