Myosin-V is a processive two-headed actin-based motor protein involved in many intracellular transport processes. A key question for understanding myosin-V function and the communication between its two heads is its behavior under load. Since in vivo myosin-V colocalizes with other much stronger motors like kinesins, its behavior under superstall forces is especially relevant. We used optical t...

The time evolution of structure factors (SF) in the disordering process of an initially phase-separated lattice depends crucially on the microscopic disordering mechanism, such as Kawasaki dynamics (KD) or vacancy-mediated disordering (VMD). Monte Carlo simulations show unexpected "dips" in the SFs. A phenomenological model is introduced to explain the dips in the odd SFs, and an analytical sol...

Proper timing of gene expression requires that transcription factors (TFs) efficiently locate and bind their target sites within a genome. Theoretical studies have long proposed that one-dimensional sliding along DNA while simultaneously reading its sequence can accelerate TF's location of target sites. Sliding by prokaryotic and eukaryotic TFs were subsequently observed. More recent theoretica...

Background. Because VO2max doesn’t provide any detailed information about aerobic examinations Oxygen Kinetic is used for more accuracy. Long intensive and repetitive exercises with sufficient time lead to increase in aerobic parameters like kinetic absorption of oxygen. Objectives. The purpose of this study was to determine time dependent effects of short-time high intensity interval...

The influence of Mo particle size on the catalytic activity and product selectivity of alkalized MoS2 nanocatalysts has been investigated. Nanocatalysts are prepared using a microemulsion technique with water-to-surfactant ratios of 1-12. Three different techniques, including XRD, TEM, and hydrogen chemisorption were used to determine the molybdenum average particle size and their activity and ...