BACKGROUND Polyamidoamine (PAMAM) and polypropylenimine (PPI) dendrimers are the commercially available and most widely used dendrimers in pharmaceutical sciences and biomedical engineering. In the present study, the loading and release behaviors of generation 3 PAMAM and generation 4 PPI dendrimers with the same amount of surface amine groups (32 per dendrimer) were compared using phenylbutazo...

C6-Fluorocarbon-dendrimer has been applied to the cotton knit fabric develop oil–water repellent, separation, acid-resistant, self-cleaning, UV-resistant, and antibacterial properties. The C6-Fluorocarbon (FC)-dendrimer-coated 100% single jersey knitted samples were prepared using “pad-dry-cure” method. 90 g/L 100 FC-dendrimer-treated fabrics showed excellent water repellency separation as well...

This paper describes the synthesis of a tri(ethylene oxide)-attached fourth-generation poly(amidoamine) dendrimer (EO3-dendrimer) and the characterization of its layers on gold. NMR analysis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry revealed that about 61 amine groups of a G4 PAMAM dendrimer were covalently conjugated with tri(ethylene oxide) units, accoun...

Dendrimer conjugates for pharmaceutical development are capable of enhancing the local delivery of cytotoxic drugs. The ability to conjugate different targeting ligands to the dendrimer allows for the cytotoxic drug to be focused at the intended target cell while minimizing collateral damage in normal cells. Dendrimers offer several advantages over other polymer conjugates by creating a better ...

G1 and G2 fluorene dendrimers with naphthalene termini were synthesized as a fluorescence turn-on type chemical sensor for vitamin K4. The fluorene dendrimers were prepared by Williamson ether reaction between the fluorene core with dihydroxy groups and dendritic naphthalene segments with methylene chloride by a convergent method. We investigated the relationship between the dendrimer generatio...

large unilamellar liposomes and multilamellar vesicles consisting of dmpc interacted with cationic phosphorus-containing dendrimers cpds g3 and g4. dsc and ζ -potential measurements have shown that liposomal-dendrimeric molecular recognition occurs due to the interaction between the complementary surface groups. calorimetric studies indicate that the enthalpy of the transition of the lipids tha...

The solution structure of complexes composed the cationic dendrimer, anionic surfactants, and their counterions is studied by molecular dynamics simulations using bead–spring coarse-grained model. We identify that depending on surfactant concentration hydrophobicity system exists in three structural regimes. In first regime molecules are noncooperatively absorbed dendrimer. Here, pervaded volum...

Electroporation is a new gene delivery method to increase gene transfer and expression in vivo. Starburst polyamidoamine dendrimers have been demonstrated to augment gene expression in vitro and in vivo. We hypothesized that the combination of electroporation and dendrimer could enhance the gene transfer and gene expression in cardiac transplants. After immersion in DNA/dendrimer complexes or i...

let g be a simple graph and (g,) denotes the number of proper vertex colourings of gwith at most  colours, which is for a fixed graph g , a polynomial in  , which is called thechromatic polynomial of g . using the chromatic polynomial of some specific graphs, weobtain the chromatic polynomials of some nanostars.