نتایج جستجو برای: denaturation

تعداد نتایج: 6710  

2011
Aditi Narendra Borkar Manoj Kumar Rout Ramakrishna V. Hosur

Protein denaturation plays a crucial role in cellular processes. In this study, denaturation of HIV-1 Protease (PR) was investigated by all-atom MD simulations in explicit solvent. The PR dimer and monomer were simulated separately in 9 M acetic acid (9 M AcOH) solution and water to study the denaturation process of PR in acetic acid environment. Direct visualization of the denaturation dynamic...

2001
Enzo Orlandini Somendra M. Bhattacharjee Davide Marenduzzo Amos Maritan Flavio Seno

Recent theoretical predictions on DNA mechanical separation induced by pulling forces are numerically tested within a model in which self-avoidance for DNA strands is fully taken into account. DNA strands are described by interacting pairs of self avoiding walks (SAW) which are pulled apart by a force applied at the two extremities. The whole phase diagram is spanned by extensive Monte Carlo (M...

Journal: :Biochemical Journal 1930

2003

The change produced in native proteins by various agents which results in loss of their characteristic properties and changes in solubility is called denaturation. The term, however, may be applied to structural and physical changes in the protein molecule which differ widely with the particular agent used. Urea denaturation differs in many respects from both heat and radiation denaturation. Ur...

Journal: :journal of physical & theoretical chemistry 2009
zohreh saadati karim zare abdol-khalegh bordbar hossein aghaie

thermal denaturation of p-iactoglobulin type b in the absence and ptencno: of g arious concentrations oftrehalo5e, sucrose and sork toles sugar osmolytes and twlyols were nuyoured hy monitoring changes in theabsorption coefficients at ph 2.0. these measurements gave aliss, or i. mpdpdint of denaturation), al-fis(enthalpy change at ty). and acp (consttun-pressure heal capaciit eh.iltgtii under a...

Journal: :The Journal of General Physiology 2003
M. L. Anson A. E. Mirsky

The denaturation of hemoglobin by salicylate in neutral solution is completely reversible. There is a mobile equilibrium between native and denatured hemoglobin in neutral salicylate solution. The higher the salicylate concentration the greater is the percentage denaturation. When there is a mobile equilibrium between the native and denatured forms of a protein, denaturation is caused by the ad...

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