In the HPTN 052 study, transmission between HIV-discordant couples was reduced by 96% when the HIV-infected partner received suppressive antiretroviral therapy (ART). We examined two transmission events where the newly infected partner was diagnosed after the HIV-infected partner (index) initiated therapy. We evaluated the sequence complexity of the viral populations and antibody reactivity in ...

Sexually transmitted infections (STIs) disproportionately affect women and create a preventable threat to their fertility. One factor that contributes to young women's high rates of STIs is reinfection from an untreated sexual partner. One way to address this problem is through expedited partner therapy, the practice of treating the sexual partners of patients in whom STIs are diagnosed. Expedi...

BACKGROUND While many cessation programs are available to assist smokers in quitting, research suggests that partner involvement may encourage long-term abstinence. OBJECTIVES The purpose of this review was to determine if an intervention to enhance partner support helps smoking cessation when added as an adjunct to a smoking cessation program. SEARCH STRATEGY The search was performed in: C...

The Placement of Aortic Transcatheter Valves (PARTNER) trial randomized inoperable patients with severe symptomatic aortic stenosis (AS) to medical therapy versus transcatheter aortic valve replacement (TAVR) in 1 arm (PARTNER B) and high-surgical-risk AS patients to surgical aortic valve replacement (SAVR) versus TAVR in the other arm (PARTNER A).1,2 TAVR was far superior to medical therapy in...

background: in radiation treatment of moving targets located in thorax region of patient body, the delivered dose does not match with the planned treatment, resulting in some over and under dosage in the tumor volume, as a function of motion magnitude and frequency. several efforts have been done to investigate the target motion effects on dose distribution in the target and surrounding normal ...

Background: in radiation treatment of moving targets located in thorax region of patient body, the delivered dose does not match with the planned treatment, resulting in some over and under dosage in the tumor volume, as a function of motion magnitude and frequency. Several efforts have been done to investigate the target motion effects on dose distribution in the target and surrounding normal ...