The conserved Bub1/Bub3 complex is recruited to the kinetochore region of mitotic chromosomes, where it initiates spindle checkpoint signaling and promotes chromosome alignment. Here we show that, in contrast to the expectation for a checkpoint pathway component, the BUB-1/BUB-3 complex promotes timely anaphase onset in Caenorhabditis elegans embryos. This activity of BUB-1/BUB-3 was independen...

beside developing strategies, success of organizations depends on alignment of strategies. one of the important functional areas in which companies develop strategies is operation. alignment of operation strategies is called horizontal alignment. the aim of this article is to present a model for alignment of operation strategies. to this end, an original algorithm has been presented by which ho...

preset study is conducted to evaluate strategic alignment between business and it in the view of organizational managers. present study has used luftman’s model on strategic alignment maturity and gartlen & shenks’ factors to promote alignment in order to evaluate alignment. research statistical population consists of managers at high education planning and research institute. no sampling is co...

Sister chromatids are often arranged as incompletely aligned entities in interphase nuclei of Arabidopsis thaliana. The STRUCTURAL MAINTENANCE OF CHROMOSOMES (SMC) 5/6 complex, together with cohesin, is involved in double-strand break (DSB) repair by sister chromatid recombination in yeasts and mammals. Here, we analyzed the function of genes in Arabidopsis. The wild-type allele of SMC5 is esse...

A new optomechanical chiral resolution scheme for molecules possessing a permanent dipole moment is proposed. The approach involves the following molecular manipulation sequence: (i) alignment electromagnetic pulse, (ii) time-delayed orienting static electric field, and (iii) scattering from frictional surface. method offers various control parameters including pulse duration intensity, field s...

Achieving business-IT alignment is one of the main purposes and also challenges of organizations. Many studies have indicated the importance of aligning information systems (IS) function with other business functions. The main purpose of this survey is evaluating business-IT alignment focusing on social and technical dimensions of business-IT alignment in Bank Mellat. The data was collected thr...

Background: In the current study, we investigated that how sagittal femoral bowing can affect the sagittal alignment ofthe femoral component in total knee arthroplasty (TKA).Methods: There were 25 patients underwent TKA. Long leg radiography in lateral view was performed. The sagittalfemoral bowing (SFB) and component alignment in relation to the sagittal mechanical axis and distal anterior cor...

Multimodal integration of visual and linguistic data is a longstanding but crucial challenge for modeling human understanding. We propose a framework that uses an unsupervised bitext alignment method to integrate visual and linguistic data. We present an empirical study of the various parameters of the framework. Our results exceed baselines using both exact and delayed temporal correspondence....