the death of a child is probably the most traumatic event any parent can experience. this tragedy is made worse if the child dies in its sleep, appar­ ently for no reason. Sudden infant death syndrome (SiDS) inevitably strikes horror into parents’ hearts; it usually happens at night and occurs in complete silence—there is no fight for life or breath to warn parents that something is horribly wr...

Background. Studies done in potential donors for heart transplantation and in experimental animals have suggested that brain death can have major histopathological and functional effects on the myocardium. Methods and Results. We developed experimental models of brain death using dogs to study the hemodynamic and catecholamine changes, the extent of myocardial structural damage, and the recover...

The mitral valve in 15 of 16 adult hearts with unclosed secundum atrial septal defects showed a consistent abnormality consisting of thickening of the medial half of the anterior cusp and some fusion of adjacent chordae. Histologically the lesion is a surface fibrosis without vascularisation or myxomatous change to suggest a rheumatic or floppy valve. The high frequency and morphological appear...

AMP-activated protein kinase (AMPK) promotes glucose transport, maintains ATP stores, and prevents injury and apoptosis during ischemia. AMPK has several direct molecular targets in the heart but also may interact with other stress-signaling pathways. This study examined the role of AMPK in the activation of the p38 mitogen-activated protein kinase (MAPK). In isolated heart muscles, the AMPK ac...

Decellularization and recellularization of hearts from newly dead donors is the latest fashion in cardiac tissue engineering. The first paper came out in 2008 in Nature Medicine (Ott et al., 2008), and news has been recently published in Nature again in July 2013 (Maher, 2013). Brendan Maher in this paper summarizes and comments on the latest important results on decellularization of a human he...

Round heart disease is a disease of unknown etiology in turkey. The objective of this study was to examinethe effect of different amounts of sodium chloride in inducing cardiomyopathy in turkey poults. There are some reports that hypoxia and furazolidone can induce cardiomyopathy in turkey. Two hundred 2-day-old turkey poults were wing-banded and placed randomly into 6 groups and 24 replicates ...

The object of the present lecture is the discussion of the group-theoretical nature of the conservation theorems for differential equations. To illustrate the use of the general conservation theorems the differential equations of mechanics are chosen.

Previous research has indicated that memories can be modified in conjunction with one’s attitudes, in particular, political beliefs. The current study extended this finding by focusing on the relationship between differing religious beliefs and false memories for news events. We predicted that religious people would be more inclined to remember fabricated news events positively depicting religi...

OBJECTIVES The aim of this study was to demonstrate safe orthotopic transplantation of porcine donor hearts harvested 24 hours after brain death and preserved for 24 hours before transplantation. DESIGN Circulatory normalization of brain dead (decapitated) pigs was obtained using a new pharmacological regimen (n = 10). The donor hearts were perfused at 8 °C in cycles of 15 min perfusion follo...