Understanding the behaviours of swimming microorganisms in various environments is important for understanding cell distribution and growth in nature and industry. However, cell behaviour in complex geometries is largely unknown. In this study, we used Tetrahymena thermophila as a model microorganism and experimentally investigated cell behaviour between two flat plates with a small angle. In t...

PURPOSE To evaluate the La autoantigen as a target for specific monoclonal antibody (mAb) binding in dead cancer cells after use of DNA-damaging chemotherapy. EXPERIMENTAL DESIGN In vitro studies of La-specific 3B9 mAb binding to malignant and normal primary cells with and without cytotoxic drug treatment were done using immunoblotting and flow cytometry. Chromatin-binding studies and immunof...

Innate immune cells are genetically conferred the ability to recognize microorganisms as "non-self", and to induce appropriate immune responses to eliminate them. On the other hand, immune cells should recognize self cells in order to avoid attacking normal tissues. For this purpose, immune cells make use of self-cell corpses. When cells undergo apoptosis, cell corpses are rapidly phagocytosed ...

Background: Ischemic stroke, as a health problem caused by the reduced blood supply to the brain, can lead to the neuronal death. The number of reliable therapies for stroke is limited. Mesenchymal stem cells (MSCs) exhibit therapeutic achievement. A major limitation of MSC application in cell therapy is the short survival span. MSCs affect target tissues through the secretion of many paracrine...

In 1981 Claude Berge asked about combinatorial properties that might be used to solve Hex puzzles. In response, we establish properties of dead, or negligible, cells in Hex and the Shannon game. A cell is dead if the colour of any stone placed there is irrelevant to the theoretical outcome of the game. We show that dead cell recognition is NPcomplete for the Shannon game; we also introduce two ...

Necrosis refers to a spectrum of morphologic changes that follow cell death in living tissue, largely resulting from the progressive degradative action enzymes on lethally injured (cells placed immediately fixative are dead but not necrotic).

introduction: different environmental factors such as drugs, ionizing radiation, etc can induce apoptosis.in the present study the effects of dose- rate and post-irradiation incubation time on gamma radiation inducedapoptosis in human breast carcinoma cell line (t-47d) (invasive ductal carcinoma) was investigated. material and methods: the t-47d cells were cultured in t25 flasks and during log ...

Blood has been the most reliable body fluid commonly used for the diagnosis of diseases. Although there have been promising investigations for the development of novel lab-on-a-chip devices to utilize other body fluids such as urine and sweat samples in diagnosis, their stability remains a problem that limits the reliability and accuracy of readouts. Hence, accurate and quantitative separation ...