نتایج جستجو برای: dbh

تعداد نتایج: 1627  

2014
I. Sakalli

In this paper, we analyze the Hawking radiation (HR) of a non-asymptotically flat (NAF) dyonic black hole (dBH) in four-dimensional (4D) Einstein-Maxwell-Dilaton (EMD) gravity by using one of the semiclassical approaches which is the so-called Hamilton-Jacobi (HJ) method. We particularly motivate on the isotropic coordinate system (ICS) of the dBH in order to highlight the ambiguity to be appea...

Journal: :Circulation 1983
M Minami H Yasuda N Yamazaki S Kojima H Nishijima N Matsumura H Togashi Y Koike H Saito

The relationship between plasma norepinephrine (NE), epinephrine (E) and dopamine-beta-hydroxylase activity (DBH) was studied in 90 cardiac patients (New York Heart Association [NYHA] classes I-IV), 85 healthy control subjects and 18 competitive skiers. The cardiac patients in NYHA classes III and IV had significantly higher NE (p less than 0.001) and lower DBH (p less than 0.001) levels than t...

Journal: :Circulation research 2014
Elizabeth S Barrie David Weinshenker Anurag Verma Sarah A Pendergrass Leslie A Lange Marylyn D Ritchie James G Wilson Helena Kuivaniemi Gerard Tromp David J Carey Glenn S Gerhard Murray H Brilliant Scott J Hebbring Joseph F Cubells Julia K Pinsonneault Greg J Norman Wolfgang Sadee

RATIONALE Dopamine β-hydroxylase (DBH) catalyzes the conversion of dopamine to norepinephrine in the central nervous system and peripherally. DBH variants are associated with large changes in circulating DBH and implicated in multiple disorders; yet causal relationships and tissue-specific effects remain unresolved. OBJECTIVE To characterize regulatory variants in DBH, effect on mRNA expressi...

2012
M. Khalilur Rahman M. Iqbal Choudhary M. Rafiqul Islam Rahman M. Hafizur

Dopoamine-β-hydroxylase (DBH) is a catecholamine-synthesizing enzyme which catalyzes the formation of norepinephrine from dopamine. Fifty nine Long-Evans rats of 1 week-old were used to grow on normal diets in 7 different developmental stages, viz., 15 rats in 1 week-old group, 9 rats in 2 weeks-old group, and the remaining 35 rats were divided equally into five groups, 7 rats in each group of ...

Journal: :Endocrinology 1999
Scott P Commins Donald J Marsh Steven A Thomas Patricia M Watson Mark A Padgett Richard Palmiter Thomas W Gettys

Exogenous leptin enhances energy utilization in ob/ob mice by binding its hypothalamic receptor and selectively increasing peripheral fat oxidation. Leptin also increases uncoupling protein 1 (UCP1) expression in brown adipose tissue (BAT), but the neurotransmitter that mediates this effect has not been established. The present experiments sought to determine whether leptin regulates UCP1 expre...

Journal: :Hypertension 1981
L X Cubeddu J Davila D Zschaeck Y R Barbella P Ordaz J Dominguez

Cerebrospinal fluid (CSF) and plasma dopamine-beta-hydroxylase (DBH) activity was measured in 22 normotensive (NT), 31 essential hypertensive (EH), and 11 renal hypertensive (RH) patients. Although no differences were observed in their plasma DBH, the mean CSF-DBH activity and specific activity of EH were significantly lower than those of NT and RH patients. Very low CSF-DBH (less than 0.15 uni...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1996
H Seo C Yang H S Kim K S Kim

The dopamine beta-hydroxylase (DBH) gene is expressed selectively in noradrenergic and adrenergic neurons and neuroendocrine cells in the nervous system. A cAMP response element (CRE) residing at -181 to -174 bp from the transcription start site of the human DBH gene seems to be essential for DBH transcription. Potential cis-regulatory motifs such as AP1 and YY1 occur proximal to and overlap th...

2010
Malin Larsson

......................................................................................................5 SAMMANFATTNING......................................................................................7 LIST OF PAPERS ...........................................................................................11 ABBREVIATIONS .......................................................................

Journal: :Addiction biology 2016
Meriem Gaval-Cruz Richard B Goertz Daniel J Puttick Dawn E Bowles Rebecca C Meyer Randy A Hall Daijin Ko Carlos A Paladini David Weinshenker

Cocaine blocks plasma membrane monoamine transporters and increases extracellular levels of dopamine (DA), norepinephrine (NE) and serotonin (5-HT). The addictive properties of cocaine are mediated primarily by DA, while NE and 5-HT play modulatory roles. Chronic inhibition of dopamine β-hydroxylase (DBH), which converts DA to NE, increases the aversive effects of cocaine and reduces cocaine us...

Journal: :Hypertension 1979
J K Huttunen J Pispa T Kumlin S Mattila V Naukkarinen T Miettinen

The activity of serum dopamine-beta-hydroxylase (DBH) was measured in 1194 asymptomatic middle-aged men with diastolic blood pressure ranging from 75 to 125 mm Hg during the baseline examination of a multifactorial intervention program for primary prevention of coronary heart disease. No correlation was present between serum DBH activity and systolic (r = -0.01, NS) or diastolic (r = +0.02, NS)...

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