The mouse mutant Doublefoot (Dbf) shows preaxial polydactyly of all four limbs. We have analysed limb development in this mutant with respect to morphogenesis, gene expression patterns and ectopic polarising activity. The results reveal a gain-of-function mutation at a locus that mediates pattern formation in the developing limb. Shh expression is identical with that of wild-type embryos, i.e. ...

Recently, deep bottleneck features (DBF) extracted from a deep neural network (DNN) containing a narrow bottleneck layer, have been applied for language identification (LID), and yield significant performance improvement over state-of-the-art methods on NIST LRE 2009. However, the DNN is trained using a large corpus of specific language which is not directly related to the LID task. More recent...

Bloom Filters (BF) [1] are space-e cient datastructures that allow membership queries from a set. In most recent years they have gained great momentum and various tweaks to them have been proposed to achieve speci c goals. Dynamic Bloom Filters (DBF) have been proposed [2] as a method to implement Bloom Filters in a scalable environment, i.e. where the nal size of a dataset is not known in adva...

Brute force attacks are used to obtain pairs of user names and passwords illegally by using all existing pairs to login to network services. These are a major security threat faced by network service administrators. In general, to prevent brute force attacks, administrators can set limitations on the number of login trials and shut down the traffic of brute force attacks with an intrusion preve...

The activity of MHC class II promoters depends upon conserved regulatory signals one of which, the extended X-box, contains in its X2 subregion a sequence related to the cAMP response element, CRE and to the TPA response element, TRE. Accordingly, X2 is recognized by the AP-1 factor and by other c-Jun or c-Fos containing heterodimers. We report that the X-box dependent promoter activity of the ...

The succession of microbial community structure and function is a central ecological topic, as microbes drive the Earth's biogeochemical cycles. To elucidate the response and mechanistic underpinnings of soil microbial community structure and metabolic potential relevant to natural forest succession, we compared soil microbial communities from three adjacent natural forests: a coniferous forest...

Dibenzo(a,e)fluoranthene (DBF), a powerful carcinogenic nonalternant aromatic hydrocarbon, has been metabolized in vitro by incubation in mouse and rat liver microsomal homogenates. Five major stable metabolites were separated by highpressure liquid chromatography and then analyzed by spectroscopic procedures and comparison with synthetic model com pounds. Three of them are phenols correspondin...

As the next generation of video coding standard, High Efficiency Video Coding (HEVC) aims to reduce 50% bit rates in comparison with previous video coding standards. In order to increase the Deblocking Filter (DBF) throughput, we propose a memory of ping-pong and interlacing VLSI architecture to prevent DBF from unnecessarily waiting for pixels in both vertical and horizontal, which only takes ...

In Qinglong ore field, the paleo-oil reservoir is found to be associated with antimony deposits, and they have a close genetic relationship. this study, aromatics geochemistry of bitumen was studied further discuss thermochemical sulfate reduction (TSR) reaction mechanism mineralization. A total 124 aromatic compounds were identified by gas chromatography–mass spectrometry (GC–MS) analysis in s...

BACKGROUND We review our single institution experience to determine predictive factors for early and delayed distant brain failure (DBF) after radiosurgery without whole brain radiotherapy (WBRT) for brain metastases. MATERIALS AND METHODS Between January 2000 and December 2010, a total of 464 patients were treated with Gamma Knife stereotactic radiosurgery (SRS) without WBRT for primary mana...