نتایج جستجو برای: das 28

تعداد نتایج: 303679  

2013
Laura Ackermann Melanie Heußner Ludger Schmidt

Für den E-Learning-Anteil einer Weiterbildung wird ein browserbasiertes Lernspiel entwickelt, welches die Weiterbildungsteilnehmer im Selbststudium nutzen sollen. Die vorliegende Ausarbeitung stellt die Evaluation des Lernspiels durch ein interdisziplinäres Expertenteam dar. Durch die Methode des lauten Denkens konnten 108 Probleme des Lernspiels aufgedeckt werden. 1 Hintergrund und Problemstel...

2013
Theresa Kabakeris Martin Geyer

Relevante Daten aus der gesamten Produktionskette von Brokkoli wurden mithilfe einer relationalen Datenbank verknüpft. Innerhalb der Wachstumsphase wurden Klimadaten und Informationen über vielfältige Kulturmaßnahmen eingebunden. Für die Qualitätsbewertung von Brokkoliköpfen kamen Chlorophyllfluoreszenzanalyse, Farbmessungen und Reflexions-spektroskopie zum Einsatz. Erste Ergebnisse zeigen, das...

Journal: :Rheumatology 2012
Elisabeth Lie Till Uhlig Désirée van der Heijde Erik Rødevand Synøve Kalstad Cecilie Kaufmann Knut Mikkelsen Tore K Kvien

OBJECTIVE To compare baseline characteristics, responses and drug survival in patients with early RA starting SSZ or MTX in a real-life setting. METHODS The analyses included DMARD-naïve patients with RA (disease duration ≤ 1 year) starting SSZ or MTX. Three- and 6-month effectiveness was compared by unadjusted analysis and with adjustment for propensity score quintile. In addition, effective...

2008
Annett Bierer Silke Meyer

Betriebliche Informationssysteme zum Produktlebenszyklusmanagement (PLM) dienen in den Unternehmen der Integration von technischer und betriebswirtschaftlicher Informationsverarbeitung. Ihnen kommt eine besondere Bedeutung für die produktbezogene Kostenschätzung im Angebotsengineering und tendenziell für das Lebenszykluskostenmanagement zu. Im vorliegenden Beitrag wird diese zentrale Rolle von ...

Journal: :Rheumatology 2003
J S Smolen F C Breedveld M H Schiff J R Kalden P Emery G Eberl P L van Riel P Tugwell

OBJECTIVE The objective of this study was to verify the usefulness of a simple disease activity index (SDAI) for rheumatoid arthritis (RA). METHODS The SDAI is the numerical sum of five outcome parameters: tender and swollen joint count (based on a 28-joint assessment), patient and physician global assessment of disease activity [visual analogue scale (VAS) 0-10 cm] and level of C-reactive pr...

Journal: :Autoimmunity 2013
Liliana Elena D'agostino Fernando Ventimiglia Juan Antonio Verna Amelia De La Colina Yanina Aguirre Alfredo Arturi Alberto Capparelli

OBJECTIVE The objective of this study was to evaluate neopterin plasma concentrations in patients with early Rheumatoid Arthritis (RA) and correlate them with disease activity. METHODS This is a 28-month prospective study carried out on 65 individuals. There were 27 patients with early RA and 38 healthy volunteers as control group. Enzyme immunoassay was used to measure concentrations of neop...

2017
François Danion Laetitia Sparsa Laurent Arnaud Ghada Alsaleh François Lefebvre Vincent Gies Thierry Martin Cédric Lukas Jean Durckel Marc Ardizzone Rose-Marie Javier Jean-François Kleinmann Paul Moreau Gilles Blaison Joelle Goetz Emmanuel Chatelus Jacques-Eric Gottenberg Jean Sibilia Christelle Sordet

Background The efficacy of antitumour necrosis factor alpha (anti-TNF-α) treatment is well recognised in rheumatoid arthritis (RA) but remains controversial in systemic lupus erythematosus (SLE). Therefore, the role of anti-TNF-α treatment in 'Rhupus', a disease sharing features of RA and SLE, is still debated. Objective To evaluate the efficacy and tolerance of anti-TNF-α in patients with rh...

Journal: :Rheumatology 2012
Alessandra Palma Pier Paolo Sainaghi Angela Amoruso Luigia Grazia Fresu Giancarlo Avanzi Mario Pirisi Sandra Brunelleschi

OBJECTIVES Peroxisome proliferator-activated receptor-gamma (PPARγ) is expressed by different cell types in the joints and plays a relevant anti-inflammatory role in various diseases. This pilot study aimed to evaluate PPARγ expression in monocytes/macrophages isolated from RA patients as compared with healthy subjects, the relationships between PPARγ expression, MMP-9 activity and disease, and...

Journal: :iranian red crescent medical journal 0
sousan kolahi connective tissue diseases research center, tabriz university of medical sciences, tabriz, ir iran hamid noshad chronic kidney diseases research center, tabriz university of medical sciences, tabriz, ir iran; chronic kidney diseases research center, tabriz university of medical sciences, tabriz, ir iran. tel: +98-9143115927 ali fakhari department of psychiatry, tabriz university of medical sciences, tabriz, ir iran ali reza khabbazi connective tissue diseases research center, tabriz university of medical sciences, tabriz, ir iran mehrzad hajaliloo connective tissue diseases research center, tabriz university of medical sciences, tabriz, ir iran leila ghahremani nasab connective tissue diseases research center, tabriz university of medical sciences, tabriz, ir iran

conclusions: this study showed that a considerable portion of patients with ra may have mental problems. the probability of these problems increased with more severe and more prolonged disease. results: ghq28 screening test showed that psychological problems were seen in 49% of studied patients. there were significant difference between duration of disease and das-28 score between the two group...

Journal: :Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2013
Shazia Zammurrad Wajahat Munir Abid Farooqi

OBJECTIVE To correlate disease activity score (DAS-28) in the patients with rheumatoid arthritis (RA) with and without secondary fibromyalgia. STUDY DESIGN Comparative cross-sectional study. PLACE AND DURATION OF STUDY Department of Rheumatology, Pakistan Institute of Medical Sciences, Islamabad, from November 2011 to April 2012. METHODOLOGY Patients aged above 16 years diagnosed to have ...

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