نتایج جستجو برای: d4

تعداد نتایج: 3479  

Journal: :Journal of Algebra 2022

We define the quantum group D4+ – a free version of demihyperoctahedral D4 (the smallest representative Coxeter series D). In order to do so, we construct analogue property that 4×4 matrix has determinant one. Such analogues determinants are usually very hard for groups in general and our result only holds size N=4. The is then defined by imposing this generalized condition on hyperoctahedral H...

Journal: :Journal of surgical oncology 2013
Hideki Takami Mitsuro Kanda Hisaharu Oya Soki Hibino Hiroyuki Sugimoto Masaya Suenaga Suguru Yamada Yoko Nishikawa Mikako Asai Tsutomu Fujii Shuji Nomoto Yasuhiro Kodera

BACKGROUND AND OBJECTIVES Though Melanoma-associated antigen (MAGE) family genes have received lots of attention as cancer-related genes and targets for immunotherapy, MAGE-D4 expression in hepatocellular carcinoma (HCC) has not yet been evaluated. METHODS MAGE-D4 mRNA expression was assayed in nine HCC cell lines and 94 HCC surgical specimens obtained from Japanese patients by quantitative r...

Journal: :Japanese Journal of Pharmacology 2000

Journal: :Molecular and biochemical parasitology 2004
Fu-Lin E Chu Eric D Lund Ellen Harvey Richard Adlof

The meront stage of the oyster protozoan parasite, Perkinsus marinus, is capable of synthesizing saturated and unsaturated fatty acids including the essential fatty acid, arachidonic acid [20:4(n-6)]. Eukaryotes employ either delta-6 (Delta-6) or delta-8 (Delta-8) desaturase pathway or both to synthesize arachidonic acid. To elucidate the arachidonic acid synthetic pathways in P. marinus, meron...

امین فرنیا مجید آنجفی

به منظور بررسی تأثیر تراکم کاشت بر خصوصیات مرفولوژیکی و عملکرد دانه ارقام سویا در استان مرکزی، آزمایشی در سال 1386 در مرکز تحقیقات کشاورزی و منابع طبیعی اراک انجام شد. آزمایش به صورت اسپلیت پلات در قالب طرح بلوک­های کامل تصادفی با سه تکرار انجام شد. عامل اصلی تراکم در چهار سطح 16=D1، 22=D2، 28=D3 و 34=D4 بوته در مترمربع و عامل فرعی شامل رقم ویلیامز=V1 و لاین جدید L17=V2بود. نتایج آزمایش نشان دا...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2012
Timothy H Witney Israt S Alam David R Turton Graham Smith Laurence Carroll Diana Brickute Frazer J Twyman Quang-Dé Nguyen Giampaolo Tomasi Ramla O Awais Eric O Aboagye

PURPOSE (11)C-Choline-positron emission tomography (PET) has been exploited to detect the aberrant choline metabolism in tumors. Radiolabeled choline uptake within the imaging time is primarily a function of transport, phosphorylation, and oxidation. Rapid choline oxidation, however, complicates interpretation of PET data. In this study, we investigated the biologic basis of the oxidation of de...

Journal: :Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2013
G Necula M Lazar A Stanescu A Pistol S Santibanez A Mankertz E Lupulescu

Molecular characterisation of measles virus is a powerful tool for tracing transmission. Genotyping may prove the absence of endemic circulation of measles virus, i.e. transmission for more than 12 months, which is one of the criteria for verifying elimination of the disease. We have genetically characterised measles viruses detected in Romania from 2008 to 2012, focusing on the recent outbreak...

Journal: :The Journal of pharmacology and experimental therapeutics 1997
S Patel S Freedman K L Chapman F Emms A E Fletcher M Knowles R Marwood G Mcallister J Myers N Curtis J J Kulagowski P D Leeson M Ridgill M Graham S Matheson D Rathbone A P Watt L J Bristow N M Rupniak E Baskin J J Lynch C I Ragan

L-745,870,(3-([4-(4-chlorophenyl)piperazin-1-yl]methyl)-1H- pyrollo[2,3-b] pyridine, was identified as a selective dopamine D4 receptor antagonist with excellent oral bioavailability and brain penetration. L-745,870 displaced specific binding of 0.2 nM [3H] spiperone to cloned human dopamine D4 receptors with a binding affinity (Ki) of 0. 43 nM which was 5- and 20-fold higher than that of the s...

Journal: :Circulation research 1988
R J Secrest B M Chapnick

Leukotriene D4 has been shown to possess the capacity to relax canine superior mesenteric and renal arterial rings in an endothelial-dependent manner. The present study was designed to determine if the remaining peptidoleukotrienes, leukotrienes C4 and E4, share this property. In addition, influences of atropine and of inhibitors of cyclooxygenase and lipoxygenase activities on relaxation produ...

Journal: :The Journal of biological chemistry 2013
Eunice Y Yuen Ping Zhong Xiangning Li Jing Wei Zhen Yan

The prefrontal cortex (PFC), a key brain region for cognitive and emotional processes, is highly regulated by dopaminergic inputs. The dopamine D4 receptor, which is enriched in PFC, has been implicated in mental disorders, such as attention deficit-hyperactivity disorder and schizophrenia. Recently we have found homeostatic regulation of AMPA receptor-mediated synaptic transmission in PFC pyra...

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