L-Oligonucleotide aptamers (Spiegelmers) consist of non-natural L-configured nucleotides and are of particular therapeutic interest due to their high resistance to plasma nucleases. The anaphylatoxin C5a, a potent inflammatory mediator generated during complement activation that has been implicated with organ damage, can be efficiently targeted by Spiegelmers. Here, we present the first crystal...

Exposure of microorganisms to high concentrations of D20 slows or stops growth, but the inhibition is often overcome after a time; in many instances, serial subculture leads to successful adaptation the many component processes of population growth, seems generally to be the most sensitive process. Shifts in the patterns of nucleic acid synthesis are sometimes seen (Flaumenhaft, Conrad, and Kat...

This paper is a reply to Barry Ickes' critique of my paper “Trust versus Illusion: What is Driving Demonetization in Russia?” in which I show that the data reject Barry Ickes' Virtual Economy explanation of barter in Russia in favor of an institutional explanation based on the lack of trust. JEL Classification: D20, G30, O10, P30

Hydrocyclones are used as pre-filter to reduce suspended particles in irrigation water on the subsequent filters. The aim of study was determine separation efficiency (SE) hydrocyclones, called H1, H2 and H3 according inlet/outlet diameters, at velocities 1.0 (V10), 1.5 (V15) 2.0 (V20) ms-1, sands diameter 0.5 (D05), (D10), (D15), (D20) 2.5 (D25) mm. Therefore, a hydrocyclone laboratory test sy...

Age at weaning affects the behaviour of piglets weaned in conventional confined environments. The adaptation of piglets to this event, which exposes piglets to important stressors, has not been examined in detail in outdoor systems. The aim of this study was to compare the behaviour of piglets weaned at 3 or 4 weeks of age in an outdoor production system. Six replicates of four piglets born and...

A method is described for the simultaneous measurement of partial specific volumes and molecular weights of proteins and other substances by sedimentation equilibrium experiments in Hz0 and D20 (or D2018) solutions. In effect, the method is a differential sedimentation equilibrium technique based upon the change produced in the equilibrium concentration distribution when the density of the solu...

The presence of the toxic cyanobacterium Microcystis in the upper San Francisco Estuary (SFE) since 1999 is a potential but to date an unquantified threat to the health and survival of aquatic organisms, such as fish and zooplankton. The microcystins (MCs) predominantly in the LR-form (MC-LR) contained in Microcystis is hepatotoxic and a potential threat to the fishery. This study was conducted...

Growth hormone (GH) and insulin-like growth factor-I (IGF-I) are closely related molecules. Insulin-like growth factor-binding protein-3 (IGFBP-3) is a main molecule that binds IGF-I. GH, IGF-I and IGFBP-3 have important roles in growth and development. In this study, we investigated the effects of exercise during pregnancy on maternal plasma levels of GH, IGF-I and IGFBP-3 and on fetal develop...

ABSTRACT: Two experiments were conducted to evaluate the effects of feeding continuously a diet containing 40% dried distillers grains with solubles (DDGS) or intermittently diets containing 20 or 40% DDGS on growth performance and carcass quality of pigs. Responses of the pigs to abrupt introduction and removal of dietary DDGS with differing concentrations of standardized ileal digestible (SID...