نتایج جستجو برای: d1a
تعداد نتایج: 185 فیلتر نتایج به سال:
nloaded DNA damage response (DDR) activates downstream pathways including cell cycle checkpoints. The D1 gene is overexpressed or amplified in many human cancers and is required for gastrointestinal, , and skin tumors in murine models. A common polymorphism in the human cyclin D1 gene is atively spliced, resulting in cyclin D1a and D1b proteins that differ in their carboxyl terminus. Cyclin ere...
The detrimental effect of climate change induced bleaching on Caribbean coral reefs has been widely documented in recent decades. Several studies have suggested that increases in the abundance of thermally tolerant endosymbionts may ameliorate the effect of climate change on reefs. Symbionts that confer tolerance to temperature also reduce the growth rate of their coral host. Here, we show, usi...
We reported previously [ Am. J. Physiol. 271 ( Renal Fluid Electrolyte Physiol. 40): F391-F400, 1996] that dopamine inhibits vasopressin (AVP)-dependent water permeability and Na+ transport in the rat cortical collecting duct (CCD) apparently through a D4 dopamine receptor. The present experiments used RT-PCR of total RNA extracted from microdissected rat CCD to determine whether the D4and D1A ...
Symbioses between nitrogen-fixing rhizobial bacteria and legumes are of great agricultural importance. We have recently-discovered a 15-amino acid peptide-hormone that contributes to root-nodule formation, essential for rhizobium-legume symbiosis. Manual application of these peptide-hormones increases nodule-formation, as does elevating activity of the corresponding gene in Medicago truncatula....
PURPOSE Alternative CCND1 splicing results in cyclin D1b, which has specialized, protumorigenic functions in prostate not shared by the cyclin D1a (full length) isoform. Here, the frequency, tumor relevance, and mechanisms controlling cyclin D1b were challenged. EXPERIMENTAL DESIGN First, relative expression of both cyclin D1 isoforms was determined in prostate adenocarcinomas. Second, releva...
Raman microspectroscopy and thermo-optical-transmittance (TOT) method were used to study airborne ambient soot collected at the suburban air monitoring station in southern Poland during residential heating (January-February) non-heating (June–July) seasons of 2017. Carbonaceous material constituted on average 47.2 wt.% PM2.5 season 26.9 season. Average concentrations OC (37.5 ± 11.0 μg/m3) EC (...
Yan, Zhen, Wen-Jie Song, and D. James Surmeier. D2 dopamine dopamine (DA) (DeBoer et al. 1993; Di Chiara et al. 1994; receptors reduce N-type Ca currents in rat neostriatal cholinergic Lehman and Langer 1983; Stoof et al. 1982), it is unclear interneurons through a membrane-delimited, protein-kinase-C-insenhow this is accomplished. sitive pathway. J. Neurophysiol. 77: 1003–1015, 1997. Dopamine ...
Reproductive stage frost poses a major constraint for wheat production in countries such as Australia. However, little progress has been made identifying key genes to overcome the constraint. In present study, severe event hit two large-scale field trials consisting of six doubled haploid (DH) populations at reproductive (young microspore stage) Western Australia, leading identification 30 robu...
The role of dopamine in the production of behaviour is multifarious in that it can influence different aspects of movement (e.g. movement initiation, sensorimotor integration, and movement sequencing). A characteristic of the dopamine system which seems to be critical for the expression of this diverse influence is its varied receptor population. Previous studies have shown that specific recept...
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