In biotin deficiency, aspartic acid becomes a limiting factor in the growth of Streptococcus faecalis ATCC 9190. Suboptimal concentrations of L-aspartate in biotin-deficient medium produce partial growth followed by lysis, which is typical of cell wall lysis due to depletion of an amino acid essential for cell wall biosynthesis. D-Aspartate, which is utilized by the cells with considerable less...

The cephalochordate amphioxus is the closest invertebrate relative to vertebrates. In this study, using HPLC technique, free L-amino acids (L-AAs) and D-aspartic acid (D-Asp) have been detected in the nervous system of the amphioxus Branchiostoma lanceolatum. Among other amino acids glutamate, aspartate, glycine, alanine and serine are the amino acids found at the greatest concentrations. As it...

1. The conductivities of aqueous solutions of glycine, d,l-valine, and l-asparagine have been determined, and comparisons have been made with similar data reported in the literature. 2. On the basis of certain theoretical considerations, calculations of the expected conductivities of aqueous solutions of glycine, asparagine, aspartic acid, and glutamic acid have been made and these data have be...

Toxin production in a large number of Pyrenophora teres isolates have been investigated. During fungal growth, the pH of the medium decreases from 6.5 to about 3.0. Aspergillomarasmine A is the major toxin excreted into the culture medium. Nonenzymatic acid-catalyzed conversion of aspergillomarasmine A to anhydroaspergillomarasmine A proceeds at low pH and is prevented by repeated titration of ...

Using molecular dynamics simulations and nuclear magnetic resonance techniques we explored the conformational preferences of linear and chiral analogs of acetyl-arginyl-glycyl-aspartic acid (Ac-RGD) and acetyl-arginyl--Alanyl-aspartic acid (Ac-RXD). Using tinker molecular modeling program and 5nano second molecular dynamics simulations in water/dimethyl sulphoxide to mimic the varying environm...

AIM The quest to identify an accurate method of age estimation, had lead to the evaluation of aspartic acid racemisation in hard tissues of the human remains using high performance liquid chromatography (HPLC). Our study is aimed at the applicability of the racemisation technique to use dentin as the sample to estimate the age in South Indian sub-population. MATERIALS AND METHODS Thirty-six n...

A fast perfusion system was used to apply excitatory amino acids to embryonic hippocampal neurons grown in dissociated culture and voltage clamped in the whole-cell recording configuration. Responses to quisqualic acid and DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid (AMPA; a potent quisqualate-like agonist) showed rapid desensitization: at 100 microM the peak inward current dec...