Early molecular events related to cytoskeleton are poorly described in Amyotrophic Lateral Sclerosis (ALS), especially in the Schwann cell (SC), which offers strong trophic support to motor neurons. Database for Annotation, Visualization and Integrated Discovery (DAVID) tool identified cytoskeleton-related genes by employing the Cellular Component Ontology (CCO) in a large gene profiling of lum...

Four of six talks in the Cytoskeleton Dynamics Minisymposium described work on filament end-binding proteins: a reflection of the central role they play in cytoskeletal organization. Scott Hansen's single-molecule study of purified vasodilator-stimulated phosphoprotein (VASP) demonstrated that it is a weakly processive actin polymerase that is targeted to filament ends by actin monomers. Hansen...

The objective of the research was to evaluate effect vitrification temperatures (VTs) and concentration cryoprotective agents (CPAs) on cytoskeleton bovine immature oocytes (BIOs). Bovine cumulus oocyte complexes (COCs) were collected divided randomly into five groups: (a) fresh control group, (b) vitrified in liquid helium (LHe; −269◦C with 5.6 M CPAs, (c) LHe (−269◦C 6.6 (d) nitrogen (LN; −19...