نتایج جستجو برای: cytokine gene polymorphism
تعداد نتایج: 1261280 فیلتر نتایج به سال:
Introduction: Estimates show that about 3-7% of all couples or women around the world have an unsolved infertility problem. Interleukin-17 (IL-17) is a pro inflammatory cytokine involved in the expression of many inflammatory mediators. The aim of this study was to investigate the relationship between (rs2275913G/A) IL-17A gene polymorphism with infertility in women. Methods: This case-control...
Introduction: Systemic lupus erythematosus (SLE) is a chronic systemic inflammatory autoimmune disease characterized by a breakdown of self-tolerance. Transforming growth factor-β1 is a cytokine produced by both immune and non immune cells, and it has a wide operating range. human TGF-β1 gene is located on chromosome 19q13 . The aim of this study was investigating the TGF-β1 Gene...
Background & Objective: Cytokines are immune system factors known to play a key role in both HCV clearance and the development of infection the impact of host genetic factors on the clinical outcome of HCV infection has not been elucidated. On the other hand, the impact of Genetic changes like Single nucleotide polymorphisms on expression rate and function of Cytokine is under study. The aim ...
Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a pathogenic element for a number of disorders. Previous studies have reported that the -1031 T/C and -238 G/A polymorphisms in the promoter region of the TNF-α gene are important factors in reproductive-related disorders. One of the most common gynecological diseases of women during the reproductive years is endo...
abstract introduction: peptic ulcer is a common problem in medicine with serious impacts on the quality of life of patients. it has been shown that helicobacter pylori infection is related with inflammatory responses of gastric mucosa. however, some patients remain asymptomatic. sustained colonization and chronic inflammation increase the risk of gastritis and peptic ulcer. the aim of this stud...
Interleukin-6 (IL6) is encoded by the IL6 gene in human and acts as pro-inflammatory cytokine and an anti-inflammatory cytokine. Recent studies established that IL6 substantially contribute in the diagnosed of systemic inflammation for the patients suffering from lung diseases such as chronic obstructive pulmonary disease (COPD). Thereof, this work aimed to investigate the prot...
background uterine leiomyoma (uls) is the most common gynecological tumor and a significant health concern for many women .the interleukin-1 receptor antagonist (il-1ra) is a naturally occurring cytokine inhibiting interleukin- 1 (il-1) activity by binding to the il-1 receptors without signal transduction. objectives the aim of this study was to investigate the association between interleukin-1...
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