نتایج جستجو برای: cytogenetics

تعداد نتایج: 10190  

Journal: :Journal of Medical Genetics 1968

2012
Kannan Thirumulu Ponnuraj

When the discovery of giant banded, salivary chromosomes in Drosophila was made by Painter in 1934, it gave a tremendous impact to the cytological work carried out in Drosophila. This made it possible to identify the chromosomes individually and also to discern the specific segments of the chromosome. Followed by this, cytogenetics bloomed with the establishment of chromosome number in man as 4...

Journal: :Briefings in functional genomics 2010
Debbie M Figueroa Hank W Bass

Plant cytogenetics has continued to flourish and make essential contributions to genomics projects by delineating marker order, defining contig gaps and revealing genome rearrangements. Here we review the field of plant cytogenetics from its conception through the eras of molecular biology and genomics. Significant advances in chromosome preparation, such as extended fiber-FISH, have greatly in...

2017
Marion Imbert-Bouteille Jean Chiesa Jean-Baptiste Gaillard Véronique Dorvaux Lucille Altounian Vincent Gatinois Eve Mousty Sanae Finge Pascal Bourquard Joris Robert Vermeesch Eric Legius Peter Vandenberghe

Medical Genetics and Cytogenetics Department, Carémeau University Hospital Center, Nîmes, France Medical Genetics and Cytogenetics Department, University Hospital Center, Montpellier, France Hematology Department, Mercy Hospital Center of Metz‐Thionville, Metz, France Cytogenetics Department, Mercy Hospital Center of Metz‐Thionville, Metz, France Multidisciplinary Prenatal Diagnosis Department,...

Journal: :Blood 2010
Miriam Miesner Claudia Haferlach Ulrike Bacher Tamara Weiss Katja Macijewski Alexander Kohlmann Hans-Ulrich Klein Martin Dugas Wolfgang Kern Susanne Schnittger Torsten Haferlach

The World Health Organization classification of acute myeloid leukemia (AML) is hierarchically structured and integrates genetics, data on patients' history, and multilineage dysplasia (MLD). The category "AML with myelodysplastic syndrome (MDS)-related changes" (AML-MRC) is separated from "AML not otherwise specified" (AML-NOS) by presence of MLD, MDS-related cytogenetics, or history of MDS or...

2017
Po‐Han Lin Huei‐Ying Li Sheng‐Chih Fan Tzu‐Hang Yuan Ming Chen Yu‐Hua Hsu Yu‐Hsuan Yang Long‐Yuan Li Su‐Peng Yeh Li‐Yuan Bai Yu‐Min Liao Chen‐Yuan Lin Ching‐Yun Hsieh Ching‐Chan Lin Che‐Hung Lin Ming‐Yu Lien Tzu‐Ting Chen Yen‐Hsuan Ni Chang‐Fang Chiu

Conventional cytogenetics can categorize patients with acute myeloid leukemia (AML) into favorable, intermediate, and unfavorable-risk groups; however, patients with intermediate-risk cytogenetics represent the major population with variable outcomes. Because molecular profiling can assist with AML prognosis and next-generation sequencing allows simultaneous sequencing of many target genes, we ...

2017
Jing SHA Fumin LIU Bei ZHANG Yang HUANG Qinglin ZHANG Gao JUAN Jingfang ZHAI

Trisomy 13 (Patau syndrome) is the third most common autosomal trisomy with a prevalence between 1 in 10,000 - 20,000 live births. Robertsonian translocations represent the largest number of chromosomal aberrations in human population with an incidence of 1.23 in 1000 live birth and translocation 13;14 is one of the most frequent Robertsonian translocations (approximately 75%). We sampled umbil...

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