A cytogenetical investigation was carried out on 8 species of amphipods from Iceland by using conventional staining, C-banding, fluorescence in situ hybridization (FISH) with rDNA and telomeric repeat probes, and flow cytometry genome size evaluation. Previously reported data on chromosome number were confirmed and the karyotype formula was determined for the first time in 3 species. The tenden...

The chemotherapeutic drugs available in the market are not specified to eliminate only cancer cells but leads to numerous toxic physical, cytogenetical and physiological side effects. Since the common target of all anticancer drugs is to decrease the growth rate (cell division) of the cancer cells, the side effects are observed in bodily systems that naturally have a rapid turnover of cells inc...

A cytogenetical study on 13 alfalfa (Medicago sativa) cultivars available in Iranian Forest and Rangelands Genebank was performed in order to obtain basic information on the variability in chiasma frequency/distribution, chromosome association and segregation. Such cytogenetic information is useful for planning hybridization programs. Cluster analysis of meiotic data and ordination of cultivars...

In yeast, the DMC1 gene is required for interhomolog recombination, which is an essential step for bivalent formation and the correct partition of chromosomes during meiosis I. By using a reverse genetics approach, we were able to identify a T-DNA insertion in AtDMC1, the Arabidopsis homolog of DMC1. Homozygotes for the AtDMC1 insertion failed to express AtDMC1, and their residual fertility was...

We examined a human gastric carcinoma cell line TMK-1 cytogenetically by G-banding technique. TMK-1 cells were characterized not only by numerical aberrations but also by structural rearrangements affecting various chromosomes. The modal chromosome number was found to be in the hypotriploid range with most ranging between 64 and 66. Flow cytometry revealed near triploid DNA histogram which was ...